N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester
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N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is an intermediate for the synthesis of N,N-Didesmethyl-O-desmethyl-(rac-Venlafaxine) Glucuronide (sc-219275). N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester is also a derivative of Venlafaxine (sc-201102). Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake. In vitro studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4.
N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N,N-Didesmethyl-O-desmethyl rac-Venlafaxine 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester, 1 mg | sc-224152 | 1 mg | $490.00 |