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N-Myristoyl-glycine (CAS 14246-55-0)

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Alternate Names:
Mryistoyl-Gly-OH
CAS Number:
14246-55-0
Molecular Weight:
285.42
Molecular Formula:
C16H31NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Myristoylglycine (NMG) is a natural amino acid derivative with well-documented biochemical and physiological effects. Although not considered essential for the body′s production, it plays a role in numerous biological functions. Found in various foods and employed in laboratory experiments, N-Myristoyl-glycine is a key component of the myristoylation process, a post-translational modification of proteins.


N-Myristoyl-glycine (CAS 14246-55-0) References

  1. A continuous assay of myristoyl-CoA:protein N-myristoyltransferase for proteomic analysis.  |  Boisson, B. and Meinnel, T. 2003. Anal Biochem. 322: 116-23. PMID: 14705787
  2. Annotation of post-translational modifications in the Swiss-Prot knowledge base.  |  Farriol-Mathis, N., et al. 2004. Proteomics. 4: 1537-50. PMID: 15174124
  3. N-myristoyltransferase: a novel target.  |  Prasad, KK., et al. 2008. Mini Rev Med Chem. 8: 142-9. PMID: 18289097
  4. Identification of glycine N-acyltransferase-like 2 (GLYATL2) as a transferase that produces N-acyl glycines in humans.  |  Waluk, DP., et al. 2010. FASEB J. 24: 2795-803. PMID: 20305126
  5. Prediction of N-myristoylation modification of proteins by SVM.  |  Cao, W., et al. 2011. Bioinformation. 6: 204-6. PMID: 21738315
  6. Antibodies to an NH2-terminal myristoyl glycine moiety can detect NH2-terminal myristoylated proteins in the retrovirus-infected cells.  |  Shoji, S., et al. 1989. Biochem Biophys Res Commun. 162: 724-32. PMID: 2547372
  7. Bioorthogonal mimetics of palmitoyl-CoA and myristoyl-CoA and their subsequent isolation by click chemistry and characterization by mass spectrometry reveal novel acylated host-proteins modified by HIV-1 infection.  |  Colquhoun, DR., et al. 2015. Proteomics. 15: 2066-77. PMID: 25914232
  8. Chemical characterization of p17gag from human immunodeficiency virus as an N-terminally myristoylated protein.  |  Goddard, C., et al. 1989. Eur J Biochem. 182: 323-6. PMID: 2737204
  9. Amino-terminal processing of proteins by N-myristoylation. Substrate specificity of N-myristoyl transferase.  |  Towler, DA., et al. 1987. J Biol Chem. 262: 1030-6. PMID: 3100524
  10. Purification and characterization of yeast myristoyl CoA:protein N-myristoyltransferase.  |  Towler, DA., et al. 1987. Proc Natl Acad Sci U S A. 84: 2708-12. PMID: 3106975
  11. Identification of N-myristoylated proteins by reverse-phase high performance liquid chromatography of an azlactone derivative of N-myristoylglycine.  |  Goddard, C. and Felsted, RL. 1988. Biochem J. 253: 839-43. PMID: 3140788
  12. SVMyr: A Web Server Detecting Co- and Post-translational Myristoylation in Proteins.  |  Madeo, G., et al. 2022. J Mol Biol. 434: 167605. PMID: 35662454
  13. Enzyme Engineering for High-Yielding Amide Formation: Lipase-Catalyzed Synthesis of N-Acyl Glycines in Aqueous Media.  |  Kua, GKB., et al. 2023. Angew Chem Int Ed Engl. 62: e202217878. PMID: 36748100
  14. A novel monoclonal antibody to N-myristoyl glycine moiety found a new N-myristoylated HIV-1 p28gag protein in HIV-1-infected cells.  |  Furuishi, K., et al. 1996. Biochem Biophys Res Commun. 222: 344-51. PMID: 8670207
  15. Inhibition of octapeptide N-myristoylation by acyl amino acids and acyl alkanolamines.  |  Tabuchi, M., et al. 1997. J Enzyme Inhib. 12: 27-36. PMID: 9204380

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Myristoyl-glycine, 50 mg

sc-286434
50 mg
$181.00

N-Myristoyl-glycine, 250 mg

sc-286434A
250 mg
$920.00