Date published: 2025-12-7

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N-Methylspiperone hydrochloride (CAS 87539-19-3)

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Alternate Names:
N-Methyl-8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro-[4.5]decan-4-one hydrochloride
Application:
CAS Number:
87539-19-3
Molecular Weight:
445.96
Molecular Formula:
C24H28FN3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Methylspiperone hydrochloride is a D2DR inhibitor, leading to decreased dopamine release and signaling. In addition, it may act to modulate the activity of several other receptors, including the 5-HT2A receptor, the 5-HT2C receptor, and the α1-adrenergic receptor. The compound is involved in a number of different processes, including memory, learning, the regulation of glutamate release, the modulation of serotonin signaling, and the modulation of adrenergic signaling.


N-Methylspiperone hydrochloride (CAS 87539-19-3) References

  1. A crystallographic and molecular modeling study of butyrophenones.  |  Liang, L., et al. 1998. J Pharm Sci. 87: 1496-501. PMID: 10189255

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Methylspiperone hydrochloride, 5 mg

sc-253121
5 mg
$112.00