N-Methylmorpholine (CAS 109-02-4)
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N-Methylmorpholine is frequently used in organic synthesis, particularly as a base in various chemical reactions. This compound is instrumental in the production of pharmaceuticals, agrochemicals, and dyes, where it acts as a catalyst or a reagent to facilitate specific transformations. Researchers utilize N-Methylmorpholine to study its efficiency and selectivity in promoting reactions, such as esterifications and the removal of protecting groups. Its role in the synthesis of complex organic molecules is critical in advancing methodologies that are more efficient and environmentally friendly. Additionally, N-Methylmorpholine is studied in the context of solvent systems, where its properties are analyzed to understand its behavior and interactions in different chemical environments, thereby contributing to the development of better reaction mediums.
N-Methylmorpholine (CAS 109-02-4) References
- Maternal and fetal toxicity of N-methylmorpholine by oral administration in rats. | Sitarek, K. 1999. Teratog Carcinog Mutagen. 19: 369-76. PMID: 10587407
- Formation of quinol co-crystals with hydrogen-bond acceptors. | Oswald, ID., et al. 2005. Acta Crystallogr B. 61: 46-57. PMID: 15659857
- The mechanism of carbon dioxide catalysis in the hydrogen peroxide N-oxidation of amines. | Balagam, B. and Richardson, DE. 2008. Inorg Chem. 47: 1173-8. PMID: 18179203
- DFT, FT-Raman, FT-IR, HOMO-LUMO and NBO studies of 4-Methylmorpholine. | Balachandran, V., et al. 2012. Spectrochim Acta A Mol Biomol Spectrosc. 97: 1101-10. PMID: 22929905
- A qualitative method for prediction of amine oxidation in methanol and water. | Bäcktorp, C., et al. 2015. J Pharm Sci. 104: 1409-20. PMID: 25712623
- The inexpensive additive N-methylmorpholine effectively decreases the equivalents of nucleophiles in the catalytic highly enantioselective arylation of aryl aldehydes. | Wang, P., et al. 2017. Chirality. 29: 443-450. PMID: 28543685
- Oscillatory Photoelectron Signal of N-Methylmorpholine as a Test Case for the Algebraic-Diagrammatic Construction Method of Second Order. | Dsouza, R., et al. 2018. J Phys Chem A. 122: 9688-9700. PMID: 30481023
- Ultrafast X-ray scattering reveals vibrational coherence following Rydberg excitation. | Stankus, B., et al. 2019. Nat Chem. 11: 716-721. PMID: 31285542
- Double C-N bond cleavages of N-alkyl 4-oxopiperidinium salts: access to unsymmetrical tertiary sulfonamides. | Fu, Y., et al. 2019. Org Biomol Chem. 17: 10172-10177. PMID: 31755519
- Rapid and Mild Lactamization Using Highly Electrophilic Triphosgene in a Microflow Reactor. | Fuse, S., et al. 2021. Chemistry. 27: 7525-7532. PMID: 33496974
- Synthesis and Aminomethylation of 2-Amino-4-(2-chlorophenyl)-6-(dicyanomethyl)-1,4-dihydropyridine-3,5-dicarbonitrile N-Methylmorpholinium Salt. | Kurskova, AO., et al. 2022. Russ J Gen Chem. 92: 779-790. PMID: 35729943
- Determination of N-methylmorpholine in air samples from a polyurethane foam factory. Comparison between two methods using gas chromatography and isotachophoresis for analysis. | Hansén, L., et al. 1986. Scand J Work Environ Health. 12: 66-9. PMID: 3961443
- Isolation of N-methylmorpholine from the seeds of Cassia occidentalis L. (coffee senna). | Kim, HL., et al. 1971. J Agric Food Chem. 19: 198-9. PMID: 5540753
- Biodegradation of N-methylmorpholine-N-oxide. | Meister, G. and Wechsler, M. 1998. Biodegradation. 9: 91-102. PMID: 9821255
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Methylmorpholine, 25 ml | sc-208047 | 25 ml | $35.00 | |||
N-Methylmorpholine, 100 ml | sc-208047A | 100 ml | $115.00 |