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N-Methyl Serotonin (CAS 1134-01-6)

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Alternate Names:
Nω-methylserotonin; Nω-methyl-5-hydroxytryptamine
Application:
N-Methyl Serotonin is a N-methylated derivative of serotonin with similar activity
CAS Number:
1134-01-6
Purity:
≥95%
Molecular Weight:
190.24
Molecular Formula:
C11H14N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Methyl serotonin is a chemical compound structurally related to the neurotransmitter serotonin. In research applications, N-Methyl serotonin is often utilized to study its binding affinity and action at serotonin receptors, exploring its role in modulating various neurotransmission pathways. The compound is of particular interest in neurochemistry, where researchers investigate its potential influence on serotoninergic systems. Additionally, it is used to understand the enzyme-catalyzed methylation processes that occur in endogenous serotonin metabolism. In environmental chemistry, N-Methyl serotonin is studied for its occurrence in natural systems and its ecological roles, as well as its potential as a natural marker for the presence of specific biological activities or processes.


N-Methyl Serotonin (CAS 1134-01-6) References

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  2. Kinetic characterization of 5-hydroxytryptamine receptor desensitization in isolated guinea-pig trachea and rabbit aorta.  |  Ben-Harari, RR., et al. 1991. J Pharmacol Exp Ther. 257: 416-24. PMID: 1850475
  3. The effects of an anabolic androgenic steroid and low serotonin on social and non-social behaviors in male rats.  |  Kubala, KH., et al. 2008. Brain Res. 1232: 21-9. PMID: 18692488
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  5. Effects of serotonin on acid secretion in isolated rat stomach: the role of 5-HT3 receptors.  |  Lai, YC., et al. 2009. Chin J Physiol. 52: 395-405. PMID: 20359130
  6. Role of serotonin in development of esophageal and gastric fundal varices.  |  Rudić, JS., et al. 2010. World J Gastroenterol. 16: 6135-8. PMID: 21182230
  7. Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism.  |  Gigliucci, V., et al. 2013. Psychopharmacology (Berl). 228: 157-66. PMID: 23455595
  8. Differences and similarities among parotoid macrogland secretions in South American toads: a preliminary biochemical delineation.  |  Sciani, JM., et al. 2013. ScientificWorldJournal. 2013: 937407. PMID: 23737734
  9. A high-performance liquid chromatography method for the serotonin release assay is equivalent to the radioactive method.  |  Sono-Koree, NK., et al. 2016. Int J Lab Hematol. 38: 72-80. PMID: 26542198
  10. Comparative Analysis of Hydrophilic Ingredients in Toad Skin and Toad Venom Using the UHPLC-HR-MS/MS and UPLC-QqQ-MS/MS Methods Together with the Anti-Inflammatory Evaluation of Indolealkylamines.  |  Zhang, Y., et al. 2018. Molecules. 24: PMID: 30591646
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  14. Platelet MAO-B activity and serotonin content in patients with dementia: effect of age, medication, and disease.  |  Mészáros, Z., et al. 1998. Neurochem Res. 23: 863-8. PMID: 9572675

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Methyl Serotonin, 100 mg

sc-391509
100 mg
$305.00