Date published: 2025-9-5

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N-Methyl-(R)-salsolinol hydrobromide

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Alternate Names:
(1R)-6,7-Dihydroxy-1,2-dimethyl-1,2,3,4-tetrahydroisoquinoline hydrobromide
Application:
N-Methyl-(R)-salsolinol hydrobromide is an endogenous neurotoxin
Purity:
≥95%
Molecular Weight:
274.15
Molecular Formula:
C11H15NO2•HBr
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Methyl-(R)-salsolinol hydrobromide is an endogenous compound that exerts neurotoxic effects specifically targeting dopaminergic neurons within the central nervous system. This compound interacts with the dopaminergic system by inducing oxidative stress and mitochondrial dysfunction, leading to neuronal degeneration. It is particularly noted for its selective affinity towards the dopaminergic neurons, making it a useful tool in neuroscientific research to study the mechanisms underlying neurodegenerative diseases such as Parkinson′s disease. Researchers utilize this compound to model these conditions in laboratory applications, allowing for the exploration of neuroprotective strategies and the understanding of dopaminergic neuronal susceptibility. Its role in neuroscientific investigations is for deciphering the complex interactions and pathological processes that characterize the degeneration of dopaminergic systems.


N-Methyl-(R)-salsolinol hydrobromide References

  1. Apoptosis induced by an endogenous neurotoxin, N-methyl(R)salsolinol, in dopamine neurons.  |  Naoi, M., et al. 2000. Toxicology. 153: 123-41. PMID: 11090952

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Methyl-(R)-salsolinol hydrobromide, 1 mg

sc-301368
1 mg
$312.00