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N-Methyl-γ-oxo-3-pyridinebutanamide (CAS 713-05-3)

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Alternate Names:
5-Hydroxycotinine; γ-(3-Pyridyl)-γ-oxo-N-methylbutyramide
Application:
N-Methyl-γ-oxo-3-pyridinebutanamide is a metabolite of Cotinine
CAS Number:
713-05-3
Molecular Weight:
192.21
Molecular Formula:
C10H12N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Methyl-γ-oxo-3-pyridinebutanamide is a compound of interest in the field of organic and medicinal chemistry due to its pyridine moiety, which is a structural component frequently found in bioactive molecules. Researchers explore the reactivity of this compound as a synthon in the synthesis of more complex heterocyclic structures, which can lead to the discovery of compounds with potential biological activity. Its ketone group is also an important functional handle that can undergo various chemical transformations, making N-Methyl-γ-oxo-3-pyridinebutanamide a versatile starting material for the construction of diverse organic compounds. In catalysis research, this compound is subject to studies involving the development of new synthetic methodologies, including enantioselective reactions, where the chirality of molecules is critical for their biological function. The compound is also employed in studies focused on the design of ligands for metal-mediated reactions, taking advantage of the nitrogen atom in the pyridine ring to coordinate to transition metals and facilitate catalytic processes.


N-Methyl-γ-oxo-3-pyridinebutanamide (CAS 713-05-3) References

  1. Screening of tobacco smoke condensate for nicotinic acetylcholine receptor ligands using cellular membrane affinity chromatography columns and missing peak chromatography.  |  Maciuk, A., et al. 2008. J Pharm Biomed Anal. 48: 238-46. PMID: 18187282
  2. Recent advances in cell membrane-coated technology for drug discovery from natural products  |  Y Bu, Q Hu, T Bao, X Xie, S Wang - TrAC Trends in Analytical Chemistry, 2022 - Elsevier. June 2022,. TrAC Trends in Analytical Chemistry. Volume 151,: 116601.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Methyl-γ-oxo-3-pyridinebutanamide, 5 mg

sc-215466
5 mg
$500.00

Interested in ordering this item, but please clarify its relation to 5-hydroxycotinine whose retention time I want to measure by LCMS. It is in equilibrium with 5-OH COT, but under what condition does it convert to 5-OH COT? I look forward to hearing from

Asked by: Keiko
Thank you for your question. It would be helpful if you could call us directly at 800-457-3801 ext.1, allowing for a more interactive discussion of this and other related questions
Answered by: Blake J
Date published: 2021-10-11
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Rated 5 out of 5 by from Fine productAn excellent chemical that could be used as a standard for LCMS analysis of cotinine metabolites in mouse plasma. Fast delivery after online purchase.
Date published: 2021-10-22
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N-Methyl-γ-oxo-3-pyridinebutanamide is rated 5.0 out of 5 by 1.
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