Date published: 2026-2-7

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N-Methyl-D-glucamine HCI (CAS 35564-86-4)

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Alternate Names:
D-Glucitol,1-deoxy-1-(methylamino)-, hydrochloride (9CI)
CAS Number:
35564-86-4
Molecular Weight:
231.67
Molecular Formula:
C7H17NO5•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Methyl-D-glucamine HCl (NMDG-HCl) is a valuable and utilized reagent in laboratory applications. It presents as a colorless, odorless crystalline powder that exhibits solubility in water. N-Methyl-D-glucamine HCl holds significant importance in biochemical and physiological investigations owing to its dual functions as a buffering agent and an ionic strength modulator. Furthermore, N-Methyl-D-glucamine HCl finds application in the synthesis of diverse compounds, encompassing pharmaceuticals and biochemicals, expanding its versatility and scientific utility.


N-Methyl-D-glucamine HCI (CAS 35564-86-4) References

  1. Cysteine scanning mutagenesis of alpha4, a putative pore-lining helix of the Bacillus thuringiensis insecticidal toxin Cry1Aa.  |  Girard, F., et al. 2008. Appl Environ Microbiol. 74: 2565-72. PMID: 18326669
  2. Advances in ventriculography and myelography with the non-ionic constrast medium metrizamide.  |  Gonsette, RE. 1976. Acta Radiol Suppl. 347: 467-76. PMID: 207136
  3. Interactions of amiloride and small monovalent cations with the epithelial sodium channel. Inferences about the nature of the channel pore.  |  Palmer, LG. and Andersen, OS. 1989. Biophys J. 55: 779-87. PMID: 2541821
  4. Effects of orotic acid and pirazetam on cortical bioelectrical activity in rabbits.  |  Krug, M., et al. 1977. Psychopharmacology (Berl). 53: 73-8. PMID: 407615
  5. Contrast media as histamine liberators. IV. In vitro mast cell histamine release by methylglucamine salts.  |  Rockoff, SD., et al. 1971. Invest Radiol. 6: 186-90. PMID: 4103863
  6. Carrier-mediated gamma-aminobutyric acid uptake in human spermatozoa indicating the presence of a high-affinity gamma-aminobutyric acid transport protein.  |  Aanesen, A., et al. 1996. Biol Reprod. 54: 841-6. PMID: 8924504

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Methyl-D-glucamine HCI, 5 g

sc-286418
5 g
$172.00

N-Methyl-D-glucamine HCI, 10 g

sc-286418A
10 g
$277.00