N-Methoxycarbonylmaleimide (CAS 55750-48-6)
QUICK LINKS
N-Methoxycarbonylmaleimide (NMCM) is a synthetic compound. In scientific research, N-Methoxycarbonylmaleimide has been employed in various experiments, specifically those pertaining to protein-protein interactions, enzyme activity, and cell signaling. Moreover, researchers have harnessed the power of N-Methoxycarbonylmaleimide to unravel the structure and function of proteins, as well as to investigate the influence of environmental factors on protein behavior. The mechanism of action of N-Methoxycarbonylmaleimide involves its role as a reversible inhibitor of protein-protein interactions. Extensive research has revealed that it binds to proteins in a non-covalent manner, mediated by hydrogen bonds and hydrophobic interactions. Additionally, N-Methoxycarbonylmaleimide has demonstrated interactions with enzymes, leading to the inhibition of specific enzyme activities.
N-Methoxycarbonylmaleimide (CAS 55750-48-6) References
- Nuclear localization signal-targeted poly(ethylene glycol) conjugates as potential carriers and nuclear localizing agents for carboplatin analogues. | Aronov, O., et al. 2004. Bioconjug Chem. 15: 814-23. PMID: 15264869
- 1-[3-(2-[18F]fluoropyridin-3-yloxy)propyl]pyrrole-2,5-dione: design, synthesis, and radiosynthesis of a new [18F]fluoropyridine-based maleimide reagent for the labeling of peptides and proteins. | de Bruin, B., et al. 2005. Bioconjug Chem. 16: 406-20. PMID: 15769096
- Radiosynthesis of new [90Y]-DOTA-based maleimide reagents suitable for the prelabeling of thiol-bearing L-oligonucleotides and peptides. | Schlesinger, J., et al. 2009. Bioconjug Chem. 20: 1340-8. PMID: 19552458
- A rhodium complex-linked β-barrel protein as a hybrid biocatalyst for phenylacetylene polymerization. | Onoda, A., et al. 2012. Chem Commun (Camb). 48: 9756-8. PMID: 22918399
- Pigment epithelium-derived factor gene loaded in cRGD-PEG-PEI suppresses colorectal cancer growth by targeting endothelial cells. | Li, L., et al. 2012. Int J Pharm. 438: 1-10. PMID: 22974524
- Development of a new thiol site-specific prosthetic group and its conjugation with [Cys(40)]-exendin-4 for in vivo targeting of insulinomas. | Yue, X., et al. 2013. Bioconjug Chem. 24: 1191-200. PMID: 23750453
- A mild synthesis of N-functionalised bromomaleimides, thiomaleimides and bromopyridazinediones. | Castañeda, L., et al. 2013. Tetrahedron Lett. 54: 3493-3495. PMID: 24058217
- Synthesis and purification of self-assembling peptide-oligonucleotide conjugates by solid-phase peptide fragment condensation. | Kye, M. and Lim, YB. 2018. J Pept Sci. 24: e3092. PMID: 29920844
- Investigation of the Diels-Alder reaction as a cross-linking mechanism for degradable poly(ethylene glycol) based hydrogels. | Kirchhof, S., et al. 2013. J Mater Chem B. 1: 4855-4864. PMID: 32261167
- Palladium-Catalyzed Site-Selective [3+2] Annulation via Benzylic and meta C-H Bond Activation. | He, Q. and Chatani, N. 2021. Angew Chem Int Ed Engl. 60: 5189-5192. PMID: 33241656
- Preparation of Maleimide-Modified Oligonucleotides from the Corresponding Amines Using N-Methoxycarbonylmaleimide. | Kjærsgaard, NL., et al. 2022. Bioconjug Chem. 33: 1254-1260. PMID: 35816757
- Combined fluorescent and gold immunoprobes: reagents and methods for correlative light and electron microscopy. | Powell, RD., et al. 1998. Microsc Res Tech. 42: 2-12. PMID: 9712158
- Multifunctional micelles for cancer cell targeting, distribution imaging, and anticancer drug delivery | Huang, C. K., Lo, C. L., Chen, H. H., & Hsiue, G. H. 2007. Advanced Functional Materials. 17(14): 2291-2297.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Methoxycarbonylmaleimide, 100 mg | sc-218971 | 100 mg | $94.00 | |||
N-Methoxycarbonylmaleimide, 1 g | sc-218971A | 1 g | $97.00 |