Date published: 2026-5-1

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N-Lauroylsarcosine (CAS 97-78-9)

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Alternate Names:
N-Dodecanoylsarcosine
CAS Number:
97-78-9
Molecular Weight:
271.40
Molecular Formula:
C15H29NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Lauroylsarcosine, also known as Lauroylsarcosine (LSC), is a versatile molecule consisting of lauroyl and sarcosine, a glycine derivative. With a broad range of applications in industry and research, N-Lauroylsarcosine serves as a surfactant, detergent, and drug delivery agent. Despite being a relatively new compound, the full extent of its capabilities remains untapped. N-Lauroylsarcosine has proven valuable in numerous scientific research endeavors, including cell culture, drug delivery, and tissue engineering. In cell culture, it acts as a surfactant to enhance cell viability and minimize cell attachment. Furthermore, N-Lauroylsarcosine demonstrates its effectiveness in stabilizing liposomes and other nanoparticles for efficient drug delivery. In the field of tissue engineering, N-Lauroylsarcosine acts as a scaffold, facilitating cellular adhesion and promoting tissue regeneration.


N-Lauroylsarcosine (CAS 97-78-9) References

  1. Thermoreversible gel formulations containing sodium lauryl sulfate or n-Lauroylsarcosine as potential topical microbicides against sexually transmitted diseases.  |  Roy, S., et al. 2001. Antimicrob Agents Chemother. 45: 1671-81. PMID: 11353610
  2. Comparative study of mechanisms of herpes simplex virus inactivation by sodium lauryl sulfate and n-lauroylsarcosine.  |  Piret, J., et al. 2002. Antimicrob Agents Chemother. 46: 2933-42. PMID: 12183250
  3. Synergistic enhancement of skin permeability by N-lauroylsarcosine and ethanol.  |  Kim, YC., et al. 2008. Int J Pharm. 352: 129-38. PMID: 18079075
  4. Pulmonary gene delivery of hybrid vector, lipopolyplex containing N-lauroylsarcosine, via the systemic route.  |  Kurosaki, T., et al. 2009. J Control Release. 136: 213-9. PMID: 19233236
  5. Facile fabrication of noble metal nanoparticles encapsulated in hollow silica with radially oriented mesopores: multiple roles of the N-lauroylsarcosine sodium surfactant.  |  Wang, H., et al. 2011. Chem Commun (Camb). 47: 7680-2. PMID: 21660319
  6. Preparative refolding of small monomeric outer membrane proteins.  |  Schwarzer, TS., et al. 2017. Protein Expr Purif. 132: 171-181. PMID: 28163214
  7. Enhanced transdermal delivery with less irritation by magainin pore-forming peptide with a N-lauroylsarcosine and sorbitan monolaurate mixture.  |  Lee, H., et al. 2018. Drug Deliv Transl Res. 8: 54-63. PMID: 29090413
  8. Fabrication of silver nanostructures using femtosecond laser-induced photoreduction.  |  Barton, P., et al. 2017. Nanotechnology. 28: 505302. PMID: 29091584
  9. Delivery of pDNA to the Lung by Lipopolyplexes Using N-Lauroylsarcosine and Effect on the Pulmonary Fibrosis.  |  Kurosaki, T., et al. 2021. Pharmaceutics. 13: PMID: 34834398
  10. Manganese in Diagnostics: A Preformulatory Study.  |  Sguizzato, M., et al. 2022. Pharmaceutics. 14: PMID: 35057004
  11. Evaluation of factors influencing expression and extraction of recombinant bacteriophage endolysins in Escherichia coli.  |  Balaban, CL., et al. 2022. Microb Cell Fact. 21: 40. PMID: 35292023
  12. High-yield production in Escherichia coli and convenient purification of a candidate vaccine against SARS-CoV-2.  |  Maltoni, G., et al. 2022. Biotechnol Lett. 44: 1313-1322. PMID: 36161539
  13. Enhanced recombinant protein capture, purity and yield from crude bacterial cell extracts by N-Lauroylsarcosine-assisted affinity chromatography.  |  Carratalá, JV., et al. 2023. Microb Cell Fact. 22: 81. PMID: 37098491

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Lauroylsarcosine, 25 g

sc-487226
25 g
$34.00