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N-Hydroxysulfosuccinimide sodium salt (CAS 106627-54-7)

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Alternate Names:
Sulfo-NHS; Hydroxy-2,3-dixopyrrolidine-3-sulfonic acid sodium salt; SNHS
Application:
CAS Number:
106627-54-7
Purity:
≥98%
Molecular Weight:
217.13
Molecular Formula:
C4H4NO6S•Na
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Hydroxysulfosuccinimide Sodium Salt is a variant of N-Hydroxysuccinimide (NHS, sc-219162), derivatized with a sulfate group to confer hydrophilicity. N-Hydroxysulfosuccinimide Sodium Salt can be utilized similarly to NHS to activate carboxylic acids of interest to the more reactive succinimidyl esters for coupling, biotinylation, and conjugation with fluorophores. Also used for crosslinking agents.


N-Hydroxysulfosuccinimide sodium salt (CAS 106627-54-7) References

  1. Succinylated polylysine as a possible link between an antibody molecule and deferoxamine.  |  Slinkin, MA., et al. 1990. Bioconjug Chem. 1: 291-5. PMID: 2096922
  2. Enhanced biocatalytic esterification with lipase-immobilized chitosan/graphene oxide beads.  |  Lau, SC., et al. 2014. PLoS One. 9: e104695. PMID: 25127038
  3. A hydrogel based nanosensor with an unprecedented broad sensitivity range for pH measurements in cellular compartments.  |  Zhang, M., et al. 2015. Analyst. 140: 7246-53. PMID: 26393332
  4. Biotinylation: a simple method for labelling complement component C8 with preservation of functional activity.  |  Bhakdi, S., et al. 1989. J Immunol Methods. 121: 61-6. PMID: 2754261
  5. Polyelectrolyte multi-layers assembly of SiCHA nanopowders and collagen type I on aminolysed PLA films to enhance cell-material interactions.  |  Baba Ismail, YM., et al. 2017. Colloids Surf B Biointerfaces. 159: 445-453. PMID: 28837894
  6. Apoptosis-promoting effect of rituximab-conjugated magnetic nanoprobes on malignant lymphoma cells with CD20 overexpression.  |  Song, L., et al. 2019. Int J Nanomedicine. 14: 921-936. PMID: 30787607
  7. Fabrication of a Biocompatible Liquid Crystal Graphene Oxide-Gold Nanorods Electro- and Photoactive Interface for Cell Stimulation.  |  Duc, D., et al. 2019. Adv Healthc Mater. 8: e1801321. PMID: 30838818
  8. The use of aggregation-induced emission probe doped silica nanoparticles for the immunoassay of human epididymis protein 4.  |  Meng, L., et al. 2019. Analyst. 144: 6136-6142. PMID: 31536063
  9. Magnetically Stimulated Drug Release Using Nanoparticles Capped by Self-Assembling Peptides.  |  Ruan, L., et al. 2019. ACS Appl Mater Interfaces. 11: 43835-43842. PMID: 31661236
  10. Preparation of a novel immunosensor for tumor biomarker detection based on ATRP technique.  |  Wang, X., et al. 2013. J Mater Chem B. 1: 2132-2138. PMID: 32260845
  11. Carboxymethyl chitosan bounded iron oxide nanoparticles and gamma-irradiated avian influenza subtype H9N2 vaccine to development of immunity on mouse and chicken.  |  Motamedi-Sedeh, F., et al. 2022. Vet Med Sci. 8: 626-634. PMID: 34878724
  12. Light-activated gold nanorods for effective therapy of venous malformation.  |  Jiang, Y., et al. 2022. Mater Today Bio. 16: 100401. PMID: 36052154
  13. Reactions of N-hydroxysulfosuccinimide active esters.  |  Anjaneyulu, PS. and Staros, JV. 1987. Int J Pept Protein Res. 30: 117-24. PMID: 3667072

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Hydroxysulfosuccinimide sodium salt, 500 mg

sc-212220
500 mg
$190.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for you question. N-Hydroxysulfosuccinimide sodium salt, sc-212220, is an off-white or white crystal.
Answered by: TechService7
Date published: 2017-02-10
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Rated 5 out of 5 by from Various publications cite the use of NVarious publications cite the use of N-Hydroxysulfosuccinimide sodium salt in applications involving conjugation and cross-linking agents. -SCBT Publication Review
Date published: 2015-01-25
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N-Hydroxysulfosuccinimide sodium salt is rated 5.0 out of 5 by 1.
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