Date published: 2025-11-3

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N-Ethyl-p-toluenesulfonamide (CAS 80-39-7)

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Alternate Names:
N-ethyl-4-methylbenzenesulfonamide
CAS Number:
80-39-7
Purity:
≥99%
Molecular Weight:
199.27
Molecular Formula:
C9H13NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Ethyl-P-toluenesulfonamide, a versatile organic compound, holds significance in compound synthesis and scientific research. It is a white crystalline solid and is soluble in water. N-Ethyl-P-toluenesulfonamide acts as an enzyme inhibitor by impeding enzyme activity through its binding to the enzyme′s active site. Additionally, it functions as an allosteric inhibitor, influencing enzyme activity by binding to a separate site on the enzyme, distinct from the active site. This compound′s multifaceted inhibitory properties make it useful in various research endeavors and synthetic processes.


N-Ethyl-p-toluenesulfonamide (CAS 80-39-7) References

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  2. Occurrence and alteration of organic contaminants in seepage and leakage water from a waste deposit landfill.  |  Schwarzbauer, J., et al. 2002. Water Res. 36: 2275-87. PMID: 12108720
  3. Highly regio- and stereoselective synthesis of alpha-(N-alkyl-N-p-toluenesulfonyl)-beta-bromo-ketones via Ni(OAc)2-catalyzed aminobromination of chalcones.  |  Sun, H., et al. 2010. Chem Biol Drug Des. 75: 269-76. PMID: 20331646
  4. Application of chemical and thermal analysis methods for studying cellulose ester plastics.  |  Schilling, M., et al. 2010. Acc Chem Res. 43: 888-96. PMID: 20455567
  5. Solvatochromic Study of Poly(vinyl chloride) Plasticizers and Their Solutions in Chloroform:  Application to Phenobarbital Partitioning and Molecular Recognition of Phenobarbital.  |  Valenta, JN., et al. 1997. Anal Chem. 69: 3490-5. PMID: 21639272
  6. Efficient tandem solid-phase extraction and liquid chromatography-triple quadrupole mass spectrometry method to determine polar benzotriazole, benzothiazole and benzenesulfonamide contaminants in environmental water samples.  |  Herrero, P., et al. 2013. J Chromatogr A. 1309: 22-32. PMID: 23972459
  7. A pressurised hot water extraction and liquid chromatography-high resolution mass spectrometry method to determine polar benzotriazole, benzothiazole and benzenesulfonamide derivates in sewage sludge.  |  Herrero, P., et al. 2014. J Chromatogr A. 1355: 53-60. PMID: 24997513
  8. Visible light-induced C3-sulfonamidation of imidazopyridines with sulfamides.  |  Gao, Y., et al. 2017. Org Biomol Chem. 15: 8102-8109. PMID: 28905975
  9. Establishment of a reference standard database for use in the qualitative and semi-quantitative analysis of pharmaceutical contact materials within an extractables survey by GC-MS.  |  Zdravkovic, SA., et al. 2018. J Pharm Biomed Anal. 151: 49-60. PMID: 29306734
  10. Suspect and Nontarget Screening for Contaminants of Emerging Concern in an Urban Estuary.  |  Tian, Z., et al. 2020. Environ Sci Technol. 54: 889-901. PMID: 31887037
  11. Prediction of Collision Cross Section Values: Application to Non-Intentionally Added Substance Identification in Food Contact Materials.  |  Song, XC., et al. 2022. J Agric Food Chem. 70: 1272-1281. PMID: 35041428
  12. Combining Passive Sampling with Suspect and Nontarget Screening to Characterize Organic Micropollutants in Streams Draining Mixed-Use Watersheds.  |  Wang, S., et al. 2022. Environ Sci Technol. 56: 16726-16736. PMID: 36331382
  13. Mutagenicity of isomeric alkanediazotates, precursors for ultimate alkylating species of carcinogenic N-nitroso compounds.  |  Ukawa-Ishikawa, S., et al. 1998. Mutat Res. 412: 99-107. PMID: 9508369

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Ethyl-p-toluenesulfonamide, 1 mg

sc-236036E
1 mg
$108.00

N-Ethyl-p-toluenesulfonamide, 10 mg

sc-236036F
10 mg
$128.00

N-Ethyl-p-toluenesulfonamide, 100 g

sc-236036
100 g
$60.00

N-Ethyl-p-toluenesulfonamide, 500 g

sc-236036A
500 g
$214.00

N-Ethyl-p-toluenesulfonamide, 1 kg

sc-236036B
1 kg
$348.00

N-Ethyl-p-toluenesulfonamide, 5 kg

sc-236036C
5 kg
$1198.00

N-Ethyl-p-toluenesulfonamide, 10 kg

sc-236036D
10 kg
$1917.00