Date published: 2025-10-18

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n-Dodecyl-β-D-maltoside (CAS 69227-93-6)

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Alternate Names:
Lauryl-β-D-maltoside; DDM
Application:
n-Dodecyl-β-D-maltoside is a water-soluble nonionic detergent composed of a maltoside sugar and aliphatic side-chain
CAS Number:
69227-93-6
Purity:
≥99%
Molecular Weight:
510.62
Molecular Formula:
C24H46O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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n-Dodecyl-beta-D-maltoside is a non-ionic surfactant compound composed of a maltoside sugar with a long aliphatic side-chain. It has been described to form useful micelles for the stabilization and solubilization of proteins. Also, it has been employed as a non-ionic surfactant in the study of membranes and membrane-bound proteins.


n-Dodecyl-β-D-maltoside (CAS 69227-93-6) References

  1. Tryptophan octyl ester in detergent micelles of dodecylmaltoside: fluorescence properties and quenching by brominated detergent analogs.  |  de Foresta, B., et al. 1999. Biophys J. 77: 3071-84. PMID: 10585929
  2. The vesicle-to-micelle transition of phosphatidylcholine vesicles induced by nonionic detergents: effects of sodium chloride, sucrose and urea.  |  Walter, A., et al. 2000. Biochim Biophys Acta. 1508: 20-33. PMID: 11090816
  3. The polar headgroup of the detergent governs the accessibility to water of tryptophan octyl ester in host micelles.  |  Tortech, L., et al. 2001. Biochim Biophys Acta. 1514: 76-86. PMID: 11513806
  4. Structure of adsorbed n-dodecyl-beta-D-maltoside layers on hematite.  |  Mielczarski, E., et al. 2004. J Colloid Interface Sci. 275: 403-9. PMID: 15178266
  5. Study of mixtures of n-dodecyl-beta-D-maltoside with anionic, cationic, and nonionic surfactant in aqueous solutions using surface tension and fluorescence techniques.  |  Zhang, R., et al. 2004. J Colloid Interface Sci. 278: 453-60. PMID: 15450466
  6. A pH-study of n-dodecyl-beta-D-maltoside foam films.  |  Stubenrauch, C., et al. 2007. Langmuir. 23: 1684-93. PMID: 17279645
  7. pH dependence of adsorption of n-dodecyl-beta-D-maltoside on solids.  |  Lu, S., et al. 2007. J Colloid Interface Sci. 316: 310-6. PMID: 17889894
  8. Mixtures of n-dodecyl-beta-D-maltoside and hexaoxyethylene dodecyl ether--surface properties, bulk properties, foam films, and foams.  |  Stubenrauch, C., et al. 2010. Adv Colloid Interface Sci. 155: 5-18. PMID: 20080225
  9. A novel membrane based process to isolate photosystem-I membrane complex from spinach.  |  Liu, J., et al. 2011. Photosynth Res. 107: 187-93. PMID: 21274629
  10. Dilational surface rheology studies of n-dodecyl-β-D-maltoside, hexaoxyethylene dodecyl ether, and their 1:1 mixture.  |  Boos, J., et al. 2013. Adv Colloid Interface Sci. 197-198: 108-17. PMID: 23726302
  11. n-Dodecyl β-D-maltoside specifically competes with general anesthetics for anesthetic binding sites.  |  Xu, L., et al. 2014. J Biomol Struct Dyn. 32: 1833-40. PMID: 24063524
  12. Synthesis of uniformly deuterated n-dodecyl-β-D-maltoside (d39-DDM) for solubilization of membrane proteins in TROSY NMR experiments.  |  Hiruma-Shimizu, K., et al. 2014. J Labelled Comp Radiopharm. 57: 737-43. PMID: 25491565
  13. The proteomic analysis of breast cell line exosomes reveals disease patterns and potential biomarkers.  |  Risha, Y., et al. 2020. Sci Rep. 10: 13572. PMID: 32782317
  14. Intersurfactant H-bonds between head groups of n-dodecyl-β-d-maltoside at the air-water interface.  |  Kanduč, M., et al. 2021. J Colloid Interface Sci. 586: 588-595. PMID: 33208246
  15. Aggregation Behavior of Sugar Surfactants in Aqueous Solutions: Effects of Temperature and the Addition of Nonionic Polymers.  |  Aoudia, M. and Zana, R. 1998. J Colloid Interface Sci. 206: 158-167. PMID: 9761639

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

n-Dodecyl-β-D-maltoside, 1 g

sc-281071
1 g
$115.00

n-Dodecyl-β-D-maltoside, 5 g

sc-281071A
5 g
$265.00
US: (Out of Stock: Availability September 12, 2025)

n-Dodecyl-β-D-maltoside, 25 g

sc-281071B
25 g
$1200.00

n-Dodecyl-β-D-maltoside, 100 g

sc-281071C
100 g
$4400.00