N-Desmethyl Dextrorphan β-D-O-Glucuronide (CAS 19153-89-0)
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N-Desmethyl Dextrorphan β-D-O-Glucuronide is a metabolite of Dextromethorphan. Initially, dextromethorphan is metabolized to dextrorphan, and then, through a process that involves the removal of a methyl group (N-desmethylation), it becomes further modified. Following this, the molecule undergoes glucuronidation, where it is bonded to glucuronic acid. This bonding significantly increases the molecule′s solubility in water. The beta-D-O-glucuronide linkage to N-desmethyl dextrorphan is critical for its elimination. This compound serves as a marker of metabolic activity, particularly in studies related to the enzymatic processes involved in metabolism and excretion. Its formation and excretion rates can provide valuable insights into the functioning of enzymes like UDP-glucuronosyltransferases (UGTs), which are pivotal in the glucuronidation process.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Desmethyl Dextrorphan β-D-O-Glucuronide, 1 mg | sc-212185 | 1 mg | $396.00 |