N-Desmethyl Clozapine-d8 hydrochloride (CAS 1189888-77-4)

N-Desmethyl Clozapine-d8 hydrochloride is a deuterated analog of the metabolite N-desmethylclozapine, specifically designed for use in analytical research applications, particularly those employing mass spectrometry or nuclear magnetic resonance spectroscopy techniques. The introduction of deuterium atoms (d8 denotes the substitution of eight hydrogen atoms with deuterium) significantly enhances the molecule′s stability and detection specificity, making it useful in pharmacokinetic and metabolic studies. This compound plays a pivotal role in the elucidation of metabolic pathways of clozapine and its analogs, providing insights into their biotransformation processes. By facilitating accurate quantification and identification of metabolites within complex biological matrices, N-Desmethyl Clozapine-d8 hydrochloride aids in advancing the understanding of the metabolic fate of similar compounds, thereby supporting the development of novel analytical methodologies and contributing to the broader field of chemical research.