N-Cyclohexanecarbonylpentadecylamine CAS: 702638-84-4
MF: C22H43NO
MW: 337.58
A selective inhibitor of acidic palmitoyl ethanolamidase.

N-Cyclohexanecarbonylpentadecylamine (CAS 702638-84-4)

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Alternate Names: N-pentadecyl-cyclohexanecarboxamide
Application: N-Cyclohexanecarbonylpentadecylamine is a selective inhibitor of acidic palmitoyl ethanolamidase
CAS Number: 702638-84-4
Molecular Weight: 337.58
Molecular Formula: C22H43NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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N-Cyclohexanecarbonylpentadecylamine is a selective inhibitor of acidic palmitoyl ethanolamidase (PEAase, IC50 = 4.5 µM). It does not, however, inhibit FAAH, even at concentrations as high as 100 µM.


References

1. Khanolkar, A D., et al., 1999. Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. Life sciences. 65(6-7): 607-16. PMID: 10462061
2. Deutsch, D G., et al., 2001. The cellular uptake of anandamide is coupled to its breakdown by fatty-acid amide hydrolase. The Journal of biological chemistry. 276(10): 6967-73. PMID: 11118429
3. Ueda, N., et al., 2001. Purification and characterization of an acid amidase selective for N-palmitoylethanolamine, a putative endogenous anti-inflammatory substance. The Journal of biological chemistry. 276(38): 35552-7. PMID: 11463796
4. Tsuboi, Kazuhito., et al., 2004. N-cyclohexanecarbonylpentadecylamine: a selective inhibitor of the acid amidase hydrolysing N-acylethanolamines, as a tool to distinguish acid amidase from fatty acid amide hydrolase. The Biochemical journal. 379(Pt 1): 99-106. PMID: 14686878

Physical State :
Solid
Storage :
Store at -20° C
Melting Point :
180.62° C (Predicted)
Boiling Point :
~480.7° C at 760 mmHg (Predicted)
Density :
~0.9 g/cm3 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
44398718
SMILES :
CCCCCCCCCCCCCCCNC(=O)C1CCCCC1

Download SDS (MSDS)

Certificate of Analysis

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