Date published: 2026-4-25

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N-(Chloroacetoxy)succinimide (CAS 27243-15-8)

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Alternate Names:
2-Chloroacetic Acid 2,5-Dioxo-1-pyrrolidinyl Ester; 2-Chloroacetic Acid N-Hydroxysuccinimide Ester
Application:
N-(Chloroacetoxy)succinimide is which is used in the preparation of organometallic complexes
CAS Number:
27243-15-8
Molecular Weight:
191.57
Molecular Formula:
C6H6ClNO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-(Chloroacetoxy)succinimide (NCAS) is an organochlorine compound used in the preparation of organometallic complexes and other synthetic probes for the labeling of proteins. It acts as an electrophilic reagent for the synthesis of peptides and amines. Additionally, N-(Chloroacetoxy)succinimide is employed in studies of enzyme kinetics, drug metabolism, cell signaling pathways, and the structure and function of proteins.


N-(Chloroacetoxy)succinimide (CAS 27243-15-8) References

  1. Structure-activity relationship of ipglycermide binding to phosphoglycerate mutases.  |  Wiedmann, M., et al. 2021. J Biol Chem. 296: 100628. PMID: 33812994
  2. Fluorescent Amino Acid Initiated de novo Cyclic Peptides for the Label-Free Assessment of Cell Permeability*.  |  Wu, Y., et al. 2021. ChemMedChem. 16: 3185-3188. PMID: 34236771

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-(Chloroacetoxy)succinimide, 1 g

sc-391642
1 g
$338.00

N-(Chloroacetoxy)succinimide, 10 g

sc-391642A
10 g
$2086.00