Date published: 2026-4-24

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N-Carboxyalanine Anhydride (CAS 2224-52-4)

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Alternate Names:
(4S)-4-Methyl-2,5-oxazolidinedione; (4S)-4-Methyl-1,3-oxazolidine-2,5-dione; (S)-4-Methyl-2,5-oxazolidinedione
CAS Number:
2224-52-4
Molecular Weight:
115.09
Molecular Formula:
C4H5NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Carboxyalanine Anhydride consists of two fused rings: an oxazolidine ring and a 2,5-dione ring. It exhibits chirality, meaning it exists as two non-superimposable mirror image forms. This characteristic makes it valuable as a reagent for synthesizing enantiomerically pure substances. N-Carboxyalanine Anhydride is employed as a reagent in the production of poly(γ-benzyl-L-glutamate) and its block polypeptides containing alanine, leucine, and phenylalanine.


N-Carboxyalanine Anhydride (CAS 2224-52-4) References

  1. Studies on the chemical basis of the antigenicity of proteins. 1. Antigenicity of polypeptidyl gelatins.  |  SELA, M. and ARNON, R. 1960. Biochem J. 75: 91-102. PMID: 14444672
  2. Enantioseparations of primary amino compounds by high-performance liquid chromatography using chiral crown ether-based chiral stationary phase.  |  Hyun, MH. 2013. Methods Mol Biol. 970: 165-76. PMID: 23283776
  3. Antibodies against polyalanyl determinants attached to negatively or positively charged carriers.  |  Licht, A., et al. 1971. Eur J Immunol. 1: 351-9. PMID: 4110257
  4. Antibody response to polyalanyl determinants in tolerant rabbits.  |  Tarrab, R., et al. 1971. Immunochemistry. 8: 1107-15. PMID: 4113504
  5. Haemagglutination-inhibition studies of the combining sites of anti-peptide antibodies in mice and rats.  |  Clerici, E., et al. 1970. Immunology. 19: 267-75. PMID: 5470195
  6. Combining sites of antibodies with L-alanine and D-alanine peptide specificity and the effect of serum proteolytic activity on their estimation.  |  Schechter, I., et al. 1966. Biochim Biophys Acta. 127: 438-56. PMID: 5964984

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Carboxyalanine Anhydride, 1 g

sc-504640
1 g
$98.00

N-Carboxyalanine Anhydride, 10 g

sc-504640A
10 g
$261.00

N-Carboxyalanine Anhydride, 25 g

sc-504640B
25 g
$516.00

N-Carboxyalanine Anhydride, 100 g

sc-504640C
100 g
$1539.00