Molecular structure of N-Boc-2-trimethylammonium-A 85380 Triflate, CAS Number: 233766-75-1
N-Boc-2-trimethylammonium-A 85380 Triflate (CAS 233766-75-1)
Application:
N-Boc-2-trimethylammonium-A 85380 Triflate is an intermediate of 2-[18F]F-A85380
CAS Number:
233766-75-1
Molecular Weight:
471.49
Molecular Formula:
C17H28N3O3•CF3SO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
An intermediate of 2-[18F]F-A85380, which is the first subtype selective PET-radiotracer to visualize the distribution of α4 2 nicotinic acetylcholine receptors in human brain in vivo.
N-Boc-2-trimethylammonium-A 85380 Triflate (CAS 233766-75-1) References
- Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: a new positron emission tomography ligand for nicotinic receptors. | Doll, F., et al. 1999. J Med Chem. 42: 2251-9. PMID: 10377231
- Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers. | Bottlaender, M., et al. 2003. J Nucl Med. 44: 596-601. PMID: 12679405
- Characterization of the human nicotinic acetylcholine receptor subunit alpha (alpha) 9 (CHRNA9) and alpha (alpha) 10 (CHRNA10) in lymphocytes. | Peng, H., et al. 2004. Life Sci. 76: 263-80. PMID: 15531379
- Nicotinic acetylcholine binding sites in Alzheimer's disease. | Whitehouse, PJ., et al. 1986. Brain Res. 371: 146-51. PMID: 3708340
- Identification of four classes of brain nicotinic receptors using beta2 mutant mice. | Zoli, M., et al. 1998. J Neurosci. 18: 4461-72. PMID: 9614223
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Boc-2-trimethylammonium-A 85380 Triflate, 5 mg | sc-207993 | 5 mg | $430.00 |