Date published: 2025-10-2

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N-Boc-2-hydroxybenzimidazole (CAS 161468-45-7)

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CAS Number:
161468-45-7
Molecular Weight:
234.25
Molecular Formula:
C12H14N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Boc-2-hydroxybenzimidazole is utilized extensively in organic synthesis research, particularly as a building block for constructing more complex organic molecules. Its Boc group (tert-butoxycarbonyl) is instrumental in protecting the nitrogen atom within the benzimidazole ring during reactions that would otherwise modify or damage this functional group. Researchers harness this stability for selective functionalization—introducing various substituents elsewhere in the molecule without disturbing the protected nitrogen. This attribute is especially critical in the synthesis of heterocycles, an area of study with relevance to materials science and catalysis, given the unique electronic properties of heterocyclic compounds. Once the desired molecular transformations are complete, the Boc group can be removed under mild conditions, allowing for the nitrogen to be further manipulated or to remain as part of the final product.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Boc-2-hydroxybenzimidazole, 250 mg

sc-286391
250 mg
$100.00

N-Boc-2-hydroxybenzimidazole, 1 g

sc-286391A
1 g
$230.00