N-Boc-1-pivaloyl-D-erythro-sphingosine (CAS 342649-71-2)

N-Boc-1-pivaloyl-D-erythro-sphingosine, identified by the CAS number 342649-71-2, is a chemically modified sphingosine, a naturally occurring sphingolipid base pivotal in the formation of complex lipids in cell membranes. This compound is characterized by the presence of protective Boc (tert-butoxycarbonyl) and pivaloyl groups. The Boc group is used to protect the amine functionality, while the pivaloyl group esterifies the primary alcohol, enhancing the compound′s stability and solubility, which are essential for its utilization in biochemical research. This synthetic derivative is extensively used in studies focusing on the synthesis and structure-activity relationships of sphingolipids. By altering specific functional groups within the sphingosine backbone, researchers can investigate the roles these modifications play in lipid-lipid and lipid-protein interactions within cellular membranes. Additionally, N-Boc-1-pivaloyl-D-erythro-sphingosine is crucial in studying the biochemical pathways of sphingolipid metabolism and their impact on cellular signaling mechanisms. The controlled introduction of such derivatives into lipid assemblies allows for the detailed exploration of sphingolipid behavior, particularly how structural changes can affect the biophysical properties of membranes and the activation of membrane-bound receptors. Hence, this compound is a valuable tool in the fundamental research of membrane dynamics and lipidomics.