Date published: 2025-12-15

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N-Biotinylcaproylaminoethyl Methanethiosulfonate (CAS 353754-95-7)

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Alternate Names:
Methanesulfonothioic Acid; MTSEA-BIOTINCAP
Application:
CAS Number:
353754-95-7
Molecular Weight:
494.69
Molecular Formula:
C19H34N4O5S3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Reacts rapidly and specifically with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABA receptor channel and of lactose permease.


N-Biotinylcaproylaminoethyl Methanethiosulfonate (CAS 353754-95-7) References

  1. Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface.  |  Snyder, PM. 2000. J Clin Invest. 105: 45-53. PMID: 10619860
  2. Gating induces a conformational change in the outer vestibule of ENaC.  |  Snyder, PM., et al. 2000. J Gen Physiol. 116: 781-90. PMID: 11099347
  3. Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.  |  Wagner, DA. and Czajkowski, C. 2001. J Neurosci. 21: 67-74. PMID: 11150321
  4. Investigating the surface expression of the renal type IIa Na+/Pi-cotransporter in Xenopus laevis oocytes.  |  Traebert, M., et al. 2001. J Membr Biol. 180: 83-90. PMID: 11284206
  5. Mutation of glutamate 155 of the GABAA receptor beta2 subunit produces a spontaneously open channel: a trigger for channel activation.  |  Newell, JG., et al. 2004. J Neurosci. 24: 11226-35. PMID: 15601928
  6. Calibrated measurement of gating-charge arginine displacement in the KvAP voltage-dependent K+ channel.  |  Ruta, V., et al. 2005. Cell. 123: 463-75. PMID: 16269337

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Biotinylcaproylaminoethyl Methanethiosulfonate, 5 mg

sc-219066
5 mg
$320.00