Molecular structure of N-(β-ketocaproyl)-L-Homoserine lactone, CAS Number: 143537-62-6
N-(β-ketocaproyl)-L-Homoserine lactone (CAS 143537-62-6)
See product citations (2)
Alternate Names:
N-(3-Oxohexanoyl)-L-homoserine lactone; 3-Oxo-C6-HSL
Application:
N-(β-ketocaproyl)-L-Homoserine lactone is a component of quorum regulatory sensing
CAS Number:
143537-62-6
Purity:
≥95%
Molecular Weight:
213.23
Molecular Formula:
C10H15NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-(β-ketocaproyl)-L-homoserine lactone is a molecule extensively studied in the context of bacterial quorum sensing, where it plays a pivotal role as an autoinducer. This compound is integral to the regulation of gene expression related to group behaviors in bacterial populations, such as biofilm development, virulence factor production, and motility. Research using N-(β-ketocaproyl)-L-homoserine lactone is critical for unraveling the complexities of bacterial communication and could inform the design of novel antibacterial strategies by targeting quorum sensing systems. Such studies are also vital for understanding the impact of microbial community interactions on human health and disease, as well as on environmental processes.
N-(β-ketocaproyl)-L-Homoserine lactone (CAS 143537-62-6) References
- Novel reporter for identification of interference with acyl homoserine lactone and autoinducer-2 quorum sensing. | Weiland-Bräuer, N., et al. 2015. Appl Environ Microbiol. 81: 1477-89. PMID: 25527543
- Plant phenolic acids affect the virulence of Pectobacterium aroidearum and P. carotovorum ssp. brasiliense via quorum sensing regulation. | Joshi, JR., et al. 2016. Mol Plant Pathol. 17: 487-500. PMID: 26177258
- Pseudomonas syringae pv. syringae B728a Regulates Multiple Stages of Plant Colonization via the Bacteriophytochrome BphP1. | McGrane, R. and Beattie, GA. 2017. mBio. 8: PMID: 29066541
- Complete Genome Sequence of an N-Acyl Homoserine Lactone Producer, Breoghania sp. Strain L-A4, Isolated from Rhizosphere of Phragmites australis in a Coastal Wetland. | He, C., et al. 2019. Microbiol Resour Announc. 8: PMID: 30714034
- Quorum Quenching Properties and Probiotic Potentials of Intestinal Associated Bacteria in Asian Sea Bass Lates calcarifer. | Ghanei-Motlagh, R., et al. 2019. Mar Drugs. 18: PMID: 31888034
- Targeted Delivery of the Mitochondrial Target Domain of Noxa to Tumor Tissue via Synthetic Secretion System in E. coli. | Lim, D., et al. 2020. Front Bioeng Biotechnol. 8: 840. PMID: 32766235
- Genetically Encoded Phase Contrast Agents for Digital Holographic Microscopy. | Farhadi, A., et al. 2020. Nano Lett. 20: 8127-8134. PMID: 33118828
- Rational engineering of a modular bacterial CRISPR-Cas activation platform with expanded target range. | Villegas Kcam, MC., et al. 2021. Nucleic Acids Res. 49: 4793-4802. PMID: 33823546
- Phloretin, an Apple Phytoalexin, Affects the Virulence and Fitness of Pectobacterium brasiliense by Interfering With Quorum-Sensing. | Pun, M., et al. 2021. Front Plant Sci. 12: 671807. PMID: 34249044
- Quorum Sensing Bacteria in the Phycosphere of HAB Microalgae and Their Ecological Functions Related to Cross-Kingdom Interactions. | Zhang, Y., et al. 2021. Int J Environ Res Public Health. 19: PMID: 35010421
- Bimodal Imaging of Tumors via Genetically Engineered Escherichia coli. | Zhang, L., et al. 2022. Pharmaceutics. 14: PMID: 36145552
- Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane. | Manioglu, S., et al. 2022. Nat Commun. 13: 6195. PMID: 36271003
- Design of combination therapy for engineered bacterial therapeutics in non-small cell lung cancer. | Deb, D., et al. 2022. Sci Rep. 12: 21551. PMID: 36513723
- Food-Grade Bacteria Combat Pathogens by Blocking AHL-Mediated Quorum Sensing and Biofilm Formation. | Savijoki, K., et al. 2022. Foods. 12: PMID: 36613306
Inhibitor of:
Chemical and Peptide Caspase.Activator of:
Edwardsiella tarda.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(β-ketocaproyl)-L-Homoserine lactone, 5 mg | sc-205396 | 5 mg | $53.00 | |||
N-(β-ketocaproyl)-L-Homoserine lactone, 25 mg | sc-205396A | 25 mg | $167.00 |