Date published: 2026-2-13

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N-Benzoyl-(2R,3S)-3-phenylisoserine (CAS 132201-33-3)

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CAS Number:
132201-33-3
Molecular Weight:
285.29
Molecular Formula:
C16H15NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Benzoyl-(2R,3S)-3-phenylisoserine is a compound of interest in organic synthesis and chiral chemistry. It is used as an intermediate in the synthesis of complex organic molecules due to its stereochemistry and functional groups. The presence of both an amino acid moiety and a protective benzoyl group makes it an important precursor in constructing peptides and other biologically relevant compounds with specific stereochemical configurations. Research involving N-Benzoyl-(2R,3S)-3-phenylisoserine often focuses on its role in the formation of carbon-carbon and carbon-nitrogen bonds, which are key steps in the production of larger chiral structures. Furthermore, the compound is utilized to study the effects of chirality on chemical reactivity and interactions, which are critical in the design of molecules with desired biological or physical properties.


N-Benzoyl-(2R,3S)-3-phenylisoserine (CAS 132201-33-3) References

  1. Highly diastereoselective enolate addition of O-protected alpha-hydroxyacetate to (S(R))-tert-butanesulfinylimines: synthesis of taxol side chain.  |  Wang, Y., et al. 2006. J Org Chem. 71: 1588-91. PMID: 16468810
  2. An investigation of nitrile transforming enzymes in the chemo-enzymatic synthesis of the taxol sidechain.  |  Wilding, B., et al. 2015. Org Biomol Chem. 13: 7803-12. PMID: 26107443
  3. Efficient and practical asymmetric synthesis of the taxol C-13 side chain, N-benzoyl-(2R, 3S)-3-phenylisoserine, and its analogs via chiral 3-hydroxy-4-aryl-. beta.-lactams through chiral ester enolate-imine cyclocondensation  |  Ojima, I., Habus, I., Zhao, M., Georg, G. I., & Jayasinghe, L. R. 1991. The Journal of Organic Chemistry. 56(5): 1681-1683.
  4. A practical chemoenzymic synthesis of the taxol C-13 side chain N-benzoyl-(2R, 3S)-3-phenylisoserine.  |  Gou, D. M., Liu, Y. C., & Chen, C. S. 1993. The Journal of Organic Chemistry,. 58(5): 1287-1289.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Benzoyl-(2R,3S)-3-phenylisoserine, 500 mg

sc-253094
500 mg
$279.00