Date published: 2025-10-19

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N-Arachidonoyl glycine (solution in ethanol) (CAS 179113-91-8)

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Alternate Names:
NAGly
Application:
N-Arachidonoyl glycine (solution in ethanol) is a compound that lacks affinity for CB1 receptors but inhibits FAAH
CAS Number:
179113-91-8
Purity:
≥98%
Molecular Weight:
361.50
Molecular Formula:
C22H35NO3
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Arachidonoyl glycine (solution in ethanol) is an endogenous anandamide-like compound. N-Arachidonoyl glycine lacks affinity for CB1 receptors (Ki > 10 μM), TRPV1 (EC50 > 10 μM) and anandamide uptake (IC50 > 50 μM), but inhibits fatty acid amide hydrolase (FAAH) (IC50 = 8.5 μM - 50 μM, depending on cell type and species).


N-Arachidonoyl glycine (solution in ethanol) (CAS 179113-91-8) References

Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor: T. Sheskin, et al.; J. Med. Chem. 40, 659 (1997) Identification of a new class of molecules, the arachidonyl amino acids, and characterization of one member that inhibits pain: S.M. Huang, et al.; J. Biol. Chem. 276, 42639 (2001) A structure-activity relationship study on N-arachidonoyl-amino acids as possible endogenous inhibitors of fatty acid amide hydrolase: M. Grazia Cascio, et al.; BBRC 314, 192 (2004)

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Arachidonoyl glycine (solution in ethanol), 5 mg

sc-203149
5 mg
$101.00