Date published: 2025-12-31

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N-Amino-D-proline (CAS 10139-05-6)

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Alternate Names:
1-Amino-D-proline
Application:
N-Amino-D-proline is a bacteriostatic agent aginst A. vinelandii
CAS Number:
10139-05-6
Molecular Weight:
130.15
Molecular Formula:
C5H10N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Amino-D-proline, a derivative of proline, is a valuable chemical compound extensively employed in peptide synthesis and pharmaceutical research. Its unique stereochemistry and amino acid backbone confer distinctive properties, making it a pivotal building block for the synthesis of peptides and bioactive compounds. In research, N-amino-D-proline serves as a chiral auxiliary in asymmetric synthesis, facilitating the construction of complex molecular architectures with high stereocontrol. Additionally, its incorporation into peptide sequences enables the modulation of peptide conformation and stability, crucial for studying structure-activity relationships and designing peptide-based probes for biological studies. Moreover, N-amino-D-proline derivatives have been investigated for their potential applications in materials science, particularly in the development of functionalized polymers and supramolecular assemblies. The precise control over stereochemistry afforded by N-amino-D-proline derivatives opens avenues for the synthesis of diverse molecular scaffolds with tailored properties, paving the way for advancements in drug discovery, catalysis, and nanotechnology. Ongoing research endeavors continue to explore novel synthetic methodologies and applications of N-amino-D-proline in diverse scientific disciplines, driving innovation and progress in chemical synthesis and materials design.


N-Amino-D-proline (CAS 10139-05-6) References

  1. Identification, characterization, and quantification of an anti-pyridoxine factor from flaxseed using ultrahigh-performance liquid chromatography-mass spectrometry.  |  Mayengbam, S., et al. 2014. J Agric Food Chem. 62: 419-26. PMID: 24354394
  2. Oral exposure to the anti-pyridoxine compound 1-amino D-proline further perturbs homocysteine metabolism through the transsulfuration pathway in moderately vitamin B₆ deficient rats.  |  Mayengbam, S., et al. 2015. J Nutr Biochem. 26: 241-9. PMID: 25524630
  3. Investigation of vitamin B₆ inadequacy, induced by exposure to the anti-B₆ factor 1-amino D-proline, on plasma lipophilic metabolites of rats: a metabolomics approach.  |  Mayengbam, S., et al. 2016. Eur J Nutr. 55: 1213-23. PMID: 26009005
  4. A Vitamin B-6 Antagonist from Flaxseed Perturbs Amino Acid Metabolism in Moderately Vitamin B-6-Deficient Male Rats.  |  Mayengbam, S., et al. 2016. J Nutr. 146: 14-20. PMID: 26581680
  5. Flaxseed Increases Animal Lifespan and Reduces Ovarian Cancer Severity by Toxically Augmenting One-Carbon Metabolism.  |  Weston, WC., et al. 2021. Molecules. 26: PMID: 34577143
  6. Isolation, characterization, and synthesis of linatine. A vitamin B6 antagonist from flaxseed (Linum usitatissimum).  |  Klosterman, HJ., et al. 1967. Biochemistry. 6: 170-7. PMID: 6071768
  7. The effects of 1-amino-D-proline on the production of carnitine from exogenous protein-bound trimethyllysine by the perfused rat liver.  |  Dunn, WA., et al. 1982. J Biol Chem. 257: 7948-51. PMID: 6806289

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Amino-D-proline, 25 mg

sc-207977A
25 mg
$302.00

N-Amino-D-proline, 50 mg

sc-207977
50 mg
$406.00

N-Amino-D-proline, 100 mg

sc-207977B
100 mg
$676.00

N-Amino-D-proline, 250 mg

sc-207977C
250 mg
$1564.00

N-Amino-D-proline, 500 mg

sc-207977D
500 mg
$2764.00