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N-Acetylprocainamide hydrochloride (CAS 34118-92-8)

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Alternate Names:
Acecainide hydrochloride
CAS Number:
34118-92-8
Molecular Weight:
313.82
Molecular Formula:
C15H23N3O2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetylprocainamide hydrochloride is a compound of interest in the field of electrophysiology, where it is used in research studies to understand the modulation of ion channels within cardiac tissues. It is particularly relevant in investigations of cardiac action potentials and the mechanisms underlying arrhythmias. Researchers may utilize N-Acetylprocainamide hydrochloride to explore its effects on ion channel kinetics and ion transport in cardiomyocytes. In addition, this compound is studied in terms of its interaction with various cardiac ion channels to elucidate the structure-activity relationships that govern channel function and pharmacology. N-Acetylprocainamide hydrochloride also serves as a tool in biochemistry research to assess the influence of N-acetyl groups on the pharmacokinetics and dynamics of related compounds.


N-Acetylprocainamide hydrochloride (CAS 34118-92-8) References

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  3. Disposition of procainamide and N-acetylprocainamide in protein-calorie malnutrition.  |  Jung, D., et al. 1985. Drug Metab Dispos. 13: 359-63. PMID: 2410212
  4. Development of high throughput screening assays and pilot screen for inhibitors of metalloproteases meprin α and β.  |  Madoux, F., et al. 2014. Biopolymers. 102: 396-406. PMID: 25048711
  5. Automated sugaring-out liquid-liquid extraction based on flow system coupled with HPLC-UV for the determination of procainamide in urine.  |  Nugbienyo, L., et al. 2017. Talanta. 167: 709-713. PMID: 28340783
  6. Flow method based on liquid-liquid extraction using deep eutectic solvent for the spectrofluorimetric determination of procainamide in human saliva.  |  Nugbienyo, L., et al. 2017. Talanta. 168: 307-312. PMID: 28391859
  7. Determination of procainamide and N-acetylprocainamide in biological fluids by high-pressure liquid chromatography.  |  Lai, CM., et al. 1980. J Pharm Sci. 69: 982-4. PMID: 6157019
  8. Pharmacokinetics of procainamide and N-acetylprocainamide in rats.  |  Kamath, BL., et al. 1981. J Pharm Sci. 70: 299-302. PMID: 6167709
  9. Development of Fluoroimmunoassays for the determination of individual or combined levels of procainamide and N-acetylprocainamide in serum.  |  Al-Hakiem, MH., et al. 1982. J Immunoassay. 3: 91-110. PMID: 6182162
  10. Age-related pharmacokinetics of N-acetylprocainamide in rats.  |  Yacobi, A., et al. 1983. J Pharm Sci. 72: 789-92. PMID: 6193264
  11. Effect of procainamide and hydralazine on poly (ADP-ribosylation) in cell lines.  |  Ayer, LM., et al. 1993. Lupus. 2: 167-72. PMID: 7690294
  12. Genotyping of N-acetylation polymorphism and correlation with procainamide metabolism.  |  Okumura, K., et al. 1997. Clin Pharmacol Ther. 61: 509-17. PMID: 9164413
  13. Direct determination of procainamide and N-acetylprocainamide by capillary zone electrophoresis in pharmaceutical formulations and urine.  |  Vargas, G., et al. 1997. J Chromatogr A. 772: 271-6. PMID: 9226929

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetylprocainamide hydrochloride, 1 g

sc-253092
1 g
$112.00