N-Acetylmuramic acid (CAS 10597-89-4)
QUICK LINKS
N-Acetylmuramic acid is a key component of bacterial cell walls, playing a role in providing structural integrity and stability to the cell. It serves as a substrate for the enzyme MurA, which is involved in the biosynthesis of peptidoglycan, a major component of the bacterial cell wall. N-Acetylmuramic acid undergoes a series of enzymatic reactions, ultimately leading to the formation of the peptide cross-links for the strength and rigidity of the cell wall. N-Acetylmuramic acid′s function is to serve as a building block for the peptidoglycan layer, contributing to the architecture and shape of the bacterial cell. Its mode of action involves participating in the synthesis of the cell wall, ultimately influencing the structural integrity and viability of the bacterial cell.
N-Acetylmuramic acid (CAS 10597-89-4) References
- Scission of the lactyl ether bond of N-acetylmuramic acid by Escherichia coli 'etherase'. | Jaeger, T., et al. 2005. J Biol Chem. 280: 30100-6. PMID: 15983044
- N-acetylmuramic acid 6-phosphate lyases (MurNAc etherases): role in cell wall metabolism, distribution, structure, and mechanism. | Jaeger, T. and Mayer, C. 2008. Cell Mol Life Sci. 65: 928-39. PMID: 18049859
- Lysozyme revisited: crystallographic evidence for distortion of an N-acetylmuramic acid residue bound in site D. | Strynadka, NC. and James, MN. 1991. J Mol Biol. 220: 401-24. PMID: 1856865
- Dependence of proliferation of Bacteroides forsythus on exogenous N-acetylmuramic acid. | Wyss, C. 1989. Infect Immun. 57: 1757-9. PMID: 2722237
- Application of 2D-ITC to the Elucidation of the Enzymatic Mechanism of N-Acetylmuramic Acid/N-Acetylglucosamine Kinase (AmgK) from Pseudomonas aeruginosa. | El-Araby, AM., et al. 2023. Biochemistry. 62: 1337-1341. PMID: 36971350
- The binding of oligosaccharides containing N-acetylglucosamine and N-acetylmuramic acid to lysozyme. The specificity of binding subsites. | Chipman, DM., et al. 1967. J Biol Chem. 242: 4388-94. PMID: 6070843
- Bacillus subtilis N-acetylmuramic acid L-alanine amidase. | Herbold, DR. and Glaser, L. 1975. J Biol Chem. 250: 1676-82. PMID: 803507
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Acetylmuramic acid, 10 mg | sc-219048 | 10 mg | $57.00 | |||
N-Acetylmuramic acid, 50 mg | sc-219048A | 50 mg | $117.00 |