Date published: 2025-12-19

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N-Acetylglycine (CAS 543-24-8)

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Alternate Names:
Acetamidoacetic acid; Aceturic acid
Application:
N-Acetylglycine is an acetylated amino acid
CAS Number:
543-24-8
Purity:
≥98%
Molecular Weight:
117.10
Molecular Formula:
C4H7NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetylglycine is a compound that functions as a precursor in the biosynthesis of proteins and other important biomolecules. It plays a role in the transfer of acetyl groups within cells, contributing to various metabolic processes. N-Acetylglycine is involved in the regulation of gene expression and the modification of proteins, impacting cellular function and signaling pathways. At the molecular level, N-Acetylglycine interacts with enzymes and coenzymes to facilitate the acetylation of specific substrates, influencing their activity and stability. Its mechanism of action involves the transfer of acetyl groups to specific molecules, affecting their structure and function within the cell.


N-Acetylglycine (CAS 543-24-8) References

  1. N-acylglycine amidation: implications for the biosynthesis of fatty acid primary amides.  |  Wilcox, BJ., et al. 1999. Biochemistry. 38: 3235-45. PMID: 10079066
  2. The identification of N-acetylglycine as a contaminant of glacial acetic acid.  |  Onge, LM., et al. 1976. Anal Biochem. 71: 156-62. PMID: 1275226
  3. Deuterium quadrupole coupling in N-acetylglycine and librational dynamics in solid poly(gamma-benzyl-L-glutamate).  |  Usha, MG., et al. 1991. Biochemistry. 30: 3955-62. PMID: 1708284
  4. Understanding the EPR parameters of glycine-derived radicals: the case of N-acetylglycyl in the N-acetylglycine single-crystal environment.  |  Kacprzak, S., et al. 2007. J Phys Chem B. 111: 811-9. PMID: 17249825
  5. Toxicology studies with N-acetylglycine.  |  Harper, MS., et al. 2010. Food Chem Toxicol. 48: 1321-7. PMID: 20188778
  6. Comparison of the conformational behavior of amino acids and N-acetylated amino acids: a theoretical and matrix-isolation FT-IR study of N-acetylglycine.  |  Boeckx, B. and Maes, G. 2012. J Phys Chem A. 116: 1956-65. PMID: 22273063
  7. Molecular structure and vibrational spectra of N-acetylglycine oligomers and polyglycine I using DFT approach.  |  Bee, S., et al. 2014. Biopolymers. 101: 795-813. PMID: 24415066
  8. N-Acetylglycine Cation Tautomerization Enabled by the Peptide Bond.  |  Kocisek, J., et al. 2015. J Phys Chem A. 119: 9581-9. PMID: 26243533
  9. Pharmacometabonomic Prediction of Busulfan Clearance in Hematopoetic Cell Transplant Recipients.  |  Navarro, SL., et al. 2016. J Proteome Res. 15: 2802-11. PMID: 27350098
  10. Catalytic properties and crystal structure of UDP-galactose 4-epimerase-like l-threonine 3-dehydrogenase from Phytophthora infestans.  |  Yoneda, K., et al. 2020. Enzyme Microb Technol. 140: 109627. PMID: 32912687
  11. Gut microbiota modulates weight gain in mice after discontinued smoke exposure.  |  Fluhr, L., et al. 2021. Nature. 600: 713-719. PMID: 34880502
  12. Formation of N-acetyl-L-alanine and N-acetylglycine from glucose by Candida tropicalis OH 23 .  |  Okuhara, M. and Harada, T. 1971. Biochim Biophys Acta. 244: 16-8. PMID: 5120213
  13. Specificity and stereospecificity of alpha-chymotrypsin.  |  Ingles, DW. and Knowles, JR. 1967. Biochem J. 104: 369-77. PMID: 6048779

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetylglycine, 5 g

sc-257828
5 g
$20.00

N-Acetylglycine, 100 g

sc-257828A
100 g
$51.00