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N-Acetyl sulfamethoxazole (CAS 21312-10-7)

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Alternate Names:
N-[4-[[(5-Methyl-3-isoxazolyl)amino]sulfonyl]phenyl]acetamide; 4′-Acetyl-3-sulfa-5-methylisoxazole; N4-Acetylsulfamethoxazole
Application:
N-Acetyl sulfamethoxazole is a sulfamethoxazole metabolite
CAS Number:
21312-10-7
Purity:
≥98%
Molecular Weight:
295.31
Molecular Formula:
C12H13N3O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetyl Sulfamethoxazole is a sulfamethoxazole metabolite. The compound has emerged as a candidate with applications in biochemistry as a reagent in organic synthesis. Its use as a reagent in organic synthesis has facilitated the creation of compounds, such as sulfonamides and amines. Furthermore, N-Acetyl sulfamethoxazole has been instrumental in showing the impacts of environmental pollutants on human health, thus aiding in the development of innovative strategies for environmental remediation.


N-Acetyl sulfamethoxazole (CAS 21312-10-7) References

  1. Biogenic metals for the oxidative and reductive removal of pharmaceuticals, biocides and iodinated contrast media in a polishing membrane bioreactor.  |  Forrez, I., et al. 2011. Water Res. 45: 1763-73. PMID: 21163512
  2. Sulfamethoxazole crystalluria.  |  Shrishrimal, K. and Wesson, J. 2011. Am J Kidney Dis. 58: 492-3. PMID: 21856494
  3. Direct photolysis of human metabolites of the antibiotic sulfamethoxazole: evidence for abiotic back-transformation.  |  Bonvin, F., et al. 2013. Environ Sci Technol. 47: 6746-55. PMID: 23186099
  4. Occurrence, seasonal variation and removal efficiency of antibiotics and their metabolites in wastewater treatment plants, Jiulongjiang River Basin, South China.  |  Zhang, H., et al. 2015. Environ Sci Process Impacts. 17: 225-34. PMID: 25503570
  5. Micropollutant degradation via extracted native enzymes from activated sludge.  |  Krah, D., et al. 2016. Water Res. 95: 348-60. PMID: 27017196
  6. Fate of sulfamethoxazole, its main metabolite N-ac-sulfamethoxazole and ciprofloxacin in agricultural soils amended or not by organic waste products.  |  Andriamalala, A., et al. 2018. Chemosphere. 191: 607-615. PMID: 29078186
  7. Impact of sludge treatments on the extractability and fate of acetyl sulfamethoxazole residues in amended soils.  |  Geng, C., et al. 2018. Chemosphere. 194: 828-836. PMID: 29268104
  8. Distribution and fate of pharmaceuticals and their metabolite conjugates in a municipal wastewater treatment plant.  |  Brown, AK. and Wong, CS. 2018. Water Res. 144: 774-783. PMID: 30176575
  9. Fate of 14C-acetyl sulfamethoxazole during the activated sludge process.  |  Geng, C., et al. 2019. Environ Sci Pollut Res Int. 26: 9832-9841. PMID: 30734913
  10. Initial Development toward Non-Invasive Drug Monitoring via Untargeted Mass Spectrometric Analysis of Human Skin.  |  Jarmusch, AK., et al. 2019. Anal Chem. 91: 8062-8069. PMID: 31074958
  11. First international quality control programme for laboratories measuring antimicrobial drugs to support dose individualization in critically ill patients.  |  Wallenburg, E., et al. 2021. J Antimicrob Chemother. 76: 430-433. PMID: 33094803
  12. Bioaccumulation of trimethoprim, sulfamethoxazole and N-acetyl-sulfamethoxazole in Artemia nauplii and residual kinetics in seabass larvae after repeated oral dosing of medicated nauplii  |  M Touraki, I Niopas, C Kastritsis -. 30 April 1999,. Aquaculture. Volume 175, Issues 1–2,: Pages 15-30.
  13. Sex-related differences in disposition of sulfamethoxazole, N-acetyl-sulfamethoxazole and trimethoprim in yellow catfish (Pelteobagrus fulvidraco) following a single oral administration  |  Y Liu, G Han, J Dong, Y Yang, Q Yang, N Xu, S Zhou…. 30 January 2021,. Aquaculture. Volume 531,: 735869.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl sulfamethoxazole, 25 mg

sc-207960
25 mg
$169.00

N-Acetyl sulfamethoxazole, 100 mg

sc-207960A
100 mg
$567.00

N-Acetyl sulfamethoxazole, 250 mg

sc-207960B
250 mg
$1367.00

i want a Certificate of Analysis sc-207960 lot I1615 it is not possible to download.... urgent

Asked by: ingriddouma
This lot-specific CoA is now available to download from our website. We have also emailed you directly.
Answered by: Technical Support
Date published: 2024-10-21

Dear sir, we need in bulk quantity. Kindly provide informatino that you have to deal in bulk or not. Best regards, Naeem Akram

Asked by: Naeem
Thank you for your question. Please contact one of our authorized distributors to request a quotation. A link to search for local distributors is provided on our website. https://www.scbt.com/scbt/resources/distributors
Answered by: Technical Support
Date published: 2016-10-28
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Rated 5 out of 5 by from Various publications cite the metabolite NVarious publications cite the metabolite N-Acetyl sulfamethoxazole as a marker of Sulfamethoxazole (sc-208405) metabolism. -SCBT Publication Review
Date published: 2015-01-30
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N-Acetyl sulfamethoxazole is rated 5.0 out of 5 by 1.
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