Molecular structure of N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide, CAS Number: 142867-52-5
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide (CAS 142867-52-5)
Application:
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide is an inhibitor of aldehyde dehydrogenase
CAS Number:
142867-52-5
Molecular Weight:
291.71
Molecular Formula:
C10H10CINO5S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide (NAC) is an organic compound belonging to the benzenesulfonamide family. This colorless, odorless crystalline solid exhibits water solubility. It serves as a reagent in organic synthesis and a catalyst in chemical reactions, while also contributing as a preservative, disinfectant, and buffering agent. N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide is speculated to function as an antioxidant and anti-inflammatory agent. It has exhibited inhibitory effects on specific enzymes, including cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX).
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide (CAS 142867-52-5) References
- N,O-diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties. | Fukuto, JM., et al. 1992. Biochem Biophys Res Commun. 187: 1367-73. PMID: 1417812
- Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase. | Lee, MJ., et al. 1992. J Med Chem. 35: 3648-52. PMID: 1433175
- Neuroprotective effects of KR-62980, a new PPARγ agonist, against chemical ischemia-reperfusion in SK-N-SH cells. | Kim, KY., et al. 2011. Brain Res. 1372: 103-14. PMID: 21111719
Inhibitor of:
ALDH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide, 10 mg | sc-203441 | 10 mg | $408.00 | |||
N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide, 50 mg | sc-203441A | 50 mg | $765.00 |