Molecular structure of N-Acetyl-L-carnosine, CAS Number: 56353-15-2
N-Acetyl-L-carnosine (CAS 56353-15-2)
Alternate Names:
N-Acetyl-L-carnosine is also known as NAC.
Application:
N-Acetyl-L-carnosine is a natural imidazole-containing dipeptide that has antioxidant activities in cells.
CAS Number:
56353-15-2
Purity:
≥98%
Molecular Weight:
268.27
Molecular Formula:
C11H16N4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
N-Acetyl-L-carnosine is a dipeptide composed of acetylated carnosine, which is of interest in biochemical research for its antioxidant properties and its ability to chelate metal ions. In studies focusing on oxidative stress and aging, this compound is utilized to investigate its potential in protecting against reactive oxygen species and its effects on cellular metabolism. N-Acetyl-L-carnosine is also studied for its role in protein glycation processes, which are relevant to understanding the biochemistry of aging tissues, especially in the context of eye health. Additionally, this compound is used as a tool in the study of muscle physiology and bioenergetics, as carnosine and its derivatives are known to be present in muscle tissue and to have roles in pH buffering. Research involving N-Acetyl-L-carnosine contributes to a broader understanding of the molecular mechanisms underlying cellular protection against oxidative damage and the maintenance of homeostasis.
N-Acetyl-L-carnosine (CAS 56353-15-2) References
- Differential neuroprotective effects of carnosine, anserine, and N-acetyl carnosine against permanent focal ischemia. | Min, J., et al. 2008. J Neurosci Res. 86: 2984-91. PMID: 18543335
- N-Acetylcarnosine and histidyl-hydrazide are potent agents for multitargeted ophthalmic therapy of senile cataracts and diabetic ocular complications. | Babizhayev, MA., et al. 2009. J Drug Target. 17: 36-63. PMID: 19037813
- Inhibitory effect of carnosine and N-acetyl carnosine on LPS-induced microglial oxidative stress and inflammation. | Fleisher-Berkovich, S., et al. 2009. Peptides. 30: 1306-12. PMID: 19540429
- A survey and analysis of the role of molecular chaperone proteins and imidazole-containing dipeptide-based compounds as molecular escorts into the skin during stress, injury, water structuring and other types of cutaneous pathophysiology. | Babizhayev, MA., et al. 2011. Int J Cosmet Sci. 33: 1-16. PMID: 20546050
- Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress. | Spina-Purrello, V., et al. 2010. Neurochem Res. 35: 2144-53. PMID: 21053069
- Dermal peptide delivery using enhancer molecules and colloidal carrier systems--part I: carnosine. | Goebel, AS., et al. 2012. Skin Pharmacol Physiol. 25: 281-7. PMID: 22890441
- Biomarkers of oxidative stress and cataract. Novel drug delivery therapeutic strategies targeting telomere reduction and the expression of telomerase activity in the lens epithelial cells with N-acetylcarnosine lubricant eye drops: anti-cataract which helps to prevent and treat cataracts in the eyes of dogs and other animals. | Babizhayev, MA. and Yegorov, YE. 2014. Curr Drug Deliv. 11: 24-61. PMID: 24783234
- Phytosome-hyaluronic acid systems for ocular delivery of L-carnosine. | Abdelkader, H., et al. 2016. Int J Nanomedicine. 11: 2815-27. PMID: 27366062
- On the Anticataractogenic Effects of L-Carnosine: Is It Best Described as an Antioxidant, Metal-Chelating Agent or Glycation Inhibitor? | Abdelkader, H., et al. 2016. Oxid Med Cell Longev. 2016: 3240261. PMID: 27822337
- Activation Effects of Carnosine- and Histidine-Containing Dipeptides on Human Carbonic Anhydrases: A Comprehensive Study. | Vistoli, G., et al. 2020. Int J Mol Sci. 21: PMID: 32143488
- Sodium Sulfite-Induced Mast Cell Pyroptosis and Degranulation. | Liu, M., et al. 2021. J Agric Food Chem. 69: 7755-7764. PMID: 34191510
- Effectuation of loading a natural acetyl carnosine derivative within a promising cross-linked cyclodextrin spongey-like nanospheres on Physicochemical characterization and release behavior. | Badawi, A., et al. 2021. Pak J Pharm Sci. 34: 283-290. PMID: 34275852
- Serum Creatine, Not Neurofilament Light, Is Elevated in CHCHD10-Linked Spinal Muscular Atrophy. | Järvilehto, J., et al. 2022. Front Neurol. 13: 793937. PMID: 35250809
- Effects of CL-1700 and its constituents on acute or chronic gastric lesions and gastric secretion in rats. | Kunimi, H. and Okabe, S. 1982. Jpn J Pharmacol. 32: 469-77. PMID: 7202068
- N alpha-acetylcarnosine is a prodrug of L-carnosine in ophthalmic application as antioxidant. | Babizhayev, MA., et al. 1996. Clin Chim Acta. 254: 1-21. PMID: 8894306
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Acetyl-L-carnosine, 100 mg | sc-219029 | 100 mg | $62.00 | |||
N-Acetyl-L-carnosine, 1 g | sc-219029A | 1 g | $100.00 | |||
N-Acetyl-L-carnosine, 10 g | sc-219029B | 10 g | $369.00 | |||
N-Acetyl-L-carnosine, 25 g | sc-219029C | 25 g | $714.00 | |||
N-Acetyl-L-carnosine, 500 g | sc-219029D | 500 g | $2086.00 | |||
N-Acetyl-L-carnosine, 1 kg | sc-219029E | 1 kg | $3713.00 |