Date published: 2026-4-25

1-800-457-3801

SCBT Portrait Logo
Seach Input

N-Acetyl-DL-homocysteine Thiolactone (CAS 17896-21-8)

0.0(0)
Write a reviewAsk a question

Alternate Names:
AHCT; Citiolone
CAS Number:
17896-21-8
Purity:
≥98%
Molecular Weight:
159.21
Molecular Formula:
C6H9NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

N-Acetyl-DL-homocysteine Thiolactone serves as a precursor in the biosynthesis of methionine and cysteine. N-Acetyl-Dl-Homocysteine Thiolactone acts as a substrate for enzymes such as cystathionine beta-synthase and cystathionine gamma-lyase, playing a role in the conversion of homocysteine to cysteine. N-Acetyl-DL-homocysteine Thiolactone is also known to be involved in the regulation of cellular redox status and the maintenance of intracellular glutathione levels.


N-Acetyl-DL-homocysteine Thiolactone (CAS 17896-21-8) References

  1. Organelle specific enzyme markers as indicators of methylmercury neurotoxicity and antidotal efficacy in mice.  |  Bapu, C., et al. 2003. Biometals. 16: 279-84. PMID: 12572686
  2. Chemical derivatives of alpha-chymotrypsinogen. III. Reaction with N-acetyl-Dl-homocysteine thiolactone.  |  ABADI, DM. and WILCOX, PE. 1960. J Biol Chem. 235: 396-404. PMID: 13791351
  3. THE REACTION OF INSULIN WITH N-ACETYL-DL-HOMOCYSTEINE THIOLACTONE: SOME CHEMICAL AND BIOLOGICAL PROPERTIES OF THE PRODUCTS.  |  VIRUPAKSHA, TK. and TARVER, H. 1964. Biochemistry. 3: 1507-11. PMID: 14230802
  4. Inability of thiol compounds to restore CNS arylsulfatases inhibited by methyl mercury.  |  Vinay, SD. and Sood, PP. 1991. Pharmacol Toxicol. 69: 71-4. PMID: 1682910
  5. Dose and duration related methylmercury deposition, glycosidases inhibition, myelin degeneration and chelation therapy.  |  Vinay, SD., et al. 1990. Cell Mol Biol. 36: 609-23. PMID: 2073685
  6. Effects of radical scavengers on the development of experimental diabetes.  |  Flechner, I., et al. 1990. Diabetes Res. 13: 67-73. PMID: 2091872
  7. A therapeutic profile of metal chelators in the detoxication of methylmercury chloride inhibited acid and alkaline phosphatases in different areas of the central nervous system of rats.  |  Vinay, SD., et al. 1989. J Environ Pathol Toxicol Oncol. 9: 351-9. PMID: 2561158
  8. Computational Study and Kinetic Analysis of the Aminolysis of Thiolactones.  |  Desmet, GB., et al. 2015. J Org Chem. 80: 8520-9. PMID: 26280542
  9. Monothiols and Vitamins are Ideal Therapeutic Agents for Mercury Elimination from Nervous and Non-Nervous Tissues of Fish.  |  Rao, AP., et al. 1998. Nutr Neurosci. 1: 383-90. PMID: 27406336
  10. Effect of N-acetyl-DL-homocysteine thiolactone and 2,3-dimercaptosuccinic acid on the restoration of alkaline phosphatase in the nervous system of rat during methylmercury toxication.  |  Sood, PP. and Unnikumar, KR. 1987. J Environ Pathol Toxicol Oncol. 7: 21-8. PMID: 3031268
  11. Methylmercury chloride-induced and antagonist-reverted succinic dehydrogenase changes in the brain and trigeminal ganglia of the rat.  |  Unnikumar, KR. and Sood, PP. 1987. Environ Res. 43: 39-47. PMID: 3034565
  12. Preparation of the bifunctional enzyme ribonuclease-deoxyribonuclease by cross-linkage.  |  Wang, D. 1979. Biochemistry. 18: 4449-52. PMID: 486431
  13. Acetylcholinesterase fluctuations in central nervous system of rat during methylmercury intoxication and chelation therapy.  |  Sood, PP., et al. 1993. J Environ Pathol Toxicol Oncol. 12: 149-54. PMID: 8189368
  14. Ameliorative capacities of vitamins and monothiols administered alone or in combinations in methylmercury mobilisation in nervous and non-nervous tissues of mice.  |  Sood, PP., et al. 1993. Cell Mol Biol (Noisy-le-grand). 39: 213-9. PMID: 8513276

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl-DL-homocysteine Thiolactone, 10 g

sc-295653
10 g
$56.00

N-Acetyl-DL-homocysteine Thiolactone, 25 g

sc-295653A
25 g
$50.00