N-Acetyl-di-O-acetyl KRP-203 (CAS 951238-25-8)
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N-Acetyl-di-O-acetyl KRP-203 has emerged as a compelling chemical compound in the scientific realm. This compound exhibits potent agonistic properties towards the sphingosine-1-phosphate receptor 1 (S1P1), a pivotal regulator of immune cell trafficking and vascular permeability. Notably, N-Acetyl-di-O-acetyl KRP-203 has demonstrated the ability to enhance the survival of oligodendrocytes, the primary producers of myelin within the central nervous system. N-Acetyl-di-O-acetyl KRP-203 are mediated through its binding and activation of the N-Acetyl-di-O-acetyl KRP-203 receptor, predominantly expressed on immune cells and endothelial cells. Subsequent receptor activation initiates internalization and degradation processes, curbing the responsiveness of immune cells to S1P gradients. Consequently, immune cells become retained within lymphoid tissues, impeding their migration to inflamed tissues.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Acetyl-di-O-acetyl KRP-203, 1 mg | sc-396030 | 1 mg | $326.00 |