Date published: 2026-4-5

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N-Acetyl Dapsone (CAS 565-20-8)

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Alternate Names:
MADDS
Application:
N-Acetyl Dapsone is a metabolite of Dapsone
CAS Number:
565-20-8
Molecular Weight:
290.34
Molecular Formula:
C14H14N2O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetyl Dapsone is an acetylated analog of dapsone that has attention in various research disciplines, particularly in the study of chemical metabolism. It is a principal metabolite of dapsone, and understanding its properties is for comprehending the metabolic fate of dapsone in the body. In chemical research, N-Acetyl Dapsone is often used as a reference compound to investigate the activity of acetyltransferase enzymes, which play a significant role in chemical metabolism. Studies involving this compound help in elucidating the pathways of biotransformation that dapsone undergoes and the implications of these pathways on the parent compound. Additionally, its stability and defined structure make N-Acetyl Dapsone an important standard in analytical assays aimed at quantifying dapsone and its metabolites in biological samples.


N-Acetyl Dapsone (CAS 565-20-8) References

  1. Hematologic safety of dapsone gel, 5%, for topical treatment of acne vulgaris.  |  Piette, WW., et al. 2008. Arch Dermatol. 144: 1564-70. PMID: 19075138
  2. Influences of Re Du Ning Injection, a traditional Chinese medicine injection, on the CYP450 activities in rats using a cocktail method.  |  Geng, T., et al. 2015. J Ethnopharmacol. 174: 426-36. PMID: 26318744
  3. Once-daily Dapsone 7.5% Gel for the Treatment of Acne Vulgaris in Preadolescent Patients: A Phase IV, Open-label, 12-week Study.  |  Moore, AY., et al. 2021. J Clin Aesthet Dermatol. 14: 43-48. PMID: 34055189
  4. Optimization, validation, and application of a liquid chromatography-tandem mass spectrometry method for the determination of 47 banned drug and related chemical residues in livestock urine using graphitized carboxyl multi-walled carbon nanotubes-based QuEChERS extraction.  |  Su, Y., et al. 2024. J Chromatogr A. 1721: 464858. PMID: 38564928
  5. Simultaneous determination of unecritinib (TQ-B3101) and its active metabolite crizotinib in rat plasma by LC-MS/MS:An application to pharmacokinetic studies.  |  Wang, H., et al. 2024. J Pharm Biomed Anal. 246: 116199. PMID: 38744200

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl Dapsone, 5 mg

sc-207954B
5 mg
$130.00

N-Acetyl Dapsone, 10 mg

sc-207954
10 mg
$213.00

N-Acetyl Dapsone, 25 mg

sc-207954A
25 mg
$505.00

N-Acetyl Dapsone, 50 mg

sc-207954C
50 mg
$837.00

N-Acetyl Dapsone, 100 mg

sc-207954D
100 mg
$1462.00