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N-Acetyl-D-galactosamine (CAS 14215-68-0)

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Alternate Names:
N-Acetylchondrosamine; 2-Acetamido-2-deoxy-D-galactose; D-GalNAc
Application:
N-Acetyl-D-galactosamine is an amino sugar derivative of galactose that is useful in forming the A blood group antigen, and is necessary for intercellular communication in nerve structures
CAS Number:
14215-68-0
Molecular Weight:
221.2
Molecular Formula:
C8H15NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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GalNAc, short for N-Acetyl-D-Galactosamine, is a monosaccharide present in numerous proteins and glycoproteins. Derived from galactose, N-Acetyl-D-Galactosamine serves as a vital constituent within the human body, contributing to various biochemical processes. Moreover, N-Acetyl-D-Galactosamine holds great significance in scientific research due to its versatile applications in laboratory experiments.. As a widely employed reagent in scientific research, N-Acetyl-D-Galactosamine facilitates the examination of protein structure, function, and cellular signaling processes. It serves as a substrate for enzymatic reactions and an inhibitor of specific enzymes. Additionally, N-Acetyl-D-Galactosamine aids in the study of carbohydrate metabolism and glycoproteins. Interactions between N-Acetyl-D-Galactosamine and proteins are thought to occur through hydrogen bonding and hydrophobic interactions. Furthermore, N-Acetyl-D-Galactosamine is believed to engage with glycosyltransferases, enzymes that catalyze the transfer of sugar molecules to proteins.


N-Acetyl-D-galactosamine (CAS 14215-68-0) References

  1. Expression of uridine diphosphate N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyl transferase 3 in adenocarcinoma of the pancreas.  |  Yamamoto, S., et al. 2004. Pathobiology. 71: 12-8. PMID: 14555840
  2. Purification and characterization of a recombinant alpha-N-acetylgalactosaminidase from Clostridium perfringens.  |  Hsieh, HY., et al. 2003. Protein Expr Purif. 32: 309-16. PMID: 14965778
  3. Carbohydrates in the cell surface of hair cells from the guinea pig cochlea.  |  Plinkert, PK., et al. 1992. Eur Arch Otorhinolaryngol. 249: 67-73. PMID: 1581047
  4. Syntheses of alpha-D-galactosamine neoglycolipids.  |  Laurent, N., et al. 2006. Carbohydr Res. 341: 823-35. PMID: 16516175
  5. Molecular characterization of pregnancy-associated plasma protein-A by electrophoresis.  |  Sinosich, MJ. 1990. Electrophoresis. 11: 70-8. PMID: 1690645
  6. Differential expression of surface glycoconjugates on Entamoeba histolytica and Entamoeba dispar.  |  Pacheco-Yépez, J., et al. 2009. Parasitol Int. 58: 171-7. PMID: 19269346
  7. Antigenic alterations in autoimmune thyroid diseases. Observations and hypotheses.  |  Wick, MR. and Sawyer, MD. 1989. Arch Pathol Lab Med. 113: 77-81. PMID: 2462859

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl-D-galactosamine, 100 mg

sc-295641
100 mg
$20.00

N-Acetyl-D-galactosamine, 500 mg

sc-295641A
500 mg
$56.00

N-Acetyl-D-galactosamine, 1 g

sc-295641B
1 g
$102.00