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N-Acetyl-5-hydroxytryptamine (CAS 1210-83-9)

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Application:
N-Acetyl-5-hydroxytryptamine is a metabolite of serotonin and a precursor of melatonin
CAS Number:
1210-83-9
Purity:
>99%
Molecular Weight:
218.3
Molecular Formula:
C12H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-Acetyl-5-hydroxytryptamine functions as a neurotransmitter and hormone in various organisms. It acts as a modulator of physiological processes, including circadian rhythms, mood, and behavior. At the molecular level, it interacts with specific receptors in the central nervous system, particularly the serotonin receptors, to regulate neurotransmission and signal transduction. N-Acetyl-5-Hydroxytryptamine also plays a role in the regulation of sleep, appetite, and stress responses. N-Acetyl-5-hydroxytryptamine is involved in the modulation of gastrointestinal function and cardiovascular activity. Its mechanism of action involves binding to specific target sites and influencing intracellular signaling pathways, ultimately impacting various physiological functions.


N-Acetyl-5-hydroxytryptamine (CAS 1210-83-9) References

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  2. Chemiluminescence determination of melatonin and some of its derivatives using potassium permanganate and formaldehyde system.  |  Chen, GN., et al. 2003. Anal Bioanal Chem. 376: 873-8. PMID: 12827333
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  7. Construction of cell factory capable of efficiently converting L-tryptophan into 5-hydroxytryptamine.  |  Wang, Y., et al. 2022. Microb Cell Fact. 21: 47. PMID: 35331215
  8. Circ-ERC2 Is Involved in Melatonin Synthesis by Regulating the miR-125a-5p/MAT2A Axis.  |  Guo, HX., et al. 2022. Int J Mol Sci. 23: PMID: 36555116
  9. Hydroxyindole-O-methyltransferase. II. Inhibitory activities of some N-acyltryptamines.  |  Ho, BT., et al. 1968. J Pharm Sci. 57: 1998-2000. PMID: 5725938
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  11. Distribution of 5-hydroxytryptamine and indolealkylamine metabolites in the American cockroach, Periplaneta americana L.  |  Sloley, BD. and Downer, RG. 1984. Comp Biochem Physiol C Comp Pharmacol Toxicol. 79: 281-6. PMID: 6083843
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  13. The determination of 5-hydroxytryptamine, related indolealkylamines and 5-hydroxyindoleacetic acid in the bovine eye by gas chromatography-negative ion chemical ionization mass spectrometry.  |  Best, SA., et al. 1993. J Pharm Biomed Anal. 11: 323-33. PMID: 7689343
  14. gamma-Glutamyl conjugation of 5-hydroxytryptamine (serotonin) in the earthworm (Lumbricus terrestris).  |  Sloley, BD. 1994. Neurochem Res. 19: 217-22. PMID: 7910382
  15. In-vivo microdialysis measurement of 5-hydroxytryptamine and its metabolites, 5-hydroxyindoleacetic acid and N-acetyl 5-hydroxytryptamine, in rat blood: effects of histamine-receptor antagonists.  |  Sakurai, E., et al. 1996. J Pharm Pharmacol. 48: 911-3. PMID: 8910852

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-Acetyl-5-hydroxytryptamine, 10 mg

sc-202716
10 mg
$20.00

N-Acetyl-5-hydroxytryptamine, 50 mg

sc-202716A
50 mg
$104.00