N-Acetyl-4-aminosalicylic Acid (CAS 50-86-2)
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N-Acetyl-4-aminosalicylic Acid (4-ASA) is an aromatic amide derivative of naturally occurring salicylic acid and has found its niche in a range of scientific and laboratory applications due to its affinity for proteins and other macromolecules. Its capacity to form covalent bonds with target molecules through a carbonyl group has rendered it a valuable asset for probing the structure and function of proteins, particularly those implicated in metabolic pathways. Additionally, N-Acetyl-4-aminosalicylic Acid aids in the examination of cellular biochemical and physiological processes, contributing to the understanding of how various substances interact with cells and organisms, and in identifying potential new molecular targets. The covalent bonds it forms are reversible, allowing for detachment from the target molecule upon bond dissociation.
N-Acetyl-4-aminosalicylic Acid (CAS 50-86-2) References
- Colonic delivery of 4-aminosalicylic acid using amylose-ethylcellulose-coated hydroxypropylmethylcellulose capsules. | Tuleu, C., et al. 2002. Aliment Pharmacol Ther. 16: 1771-9. PMID: 12269970
- Bacteria and pH-sensitive polysaccharide-polymer films for colon targeted delivery. | Esseku, F. and Adeyeye, MC. 2011. Crit Rev Ther Drug Carrier Syst. 28: 395-445. PMID: 22077200
- Salicylates are interference compounds in TR-FRET assays. | Hanley, RP., et al. 2016. Bioorg Med Chem Lett. 26: 973-977. PMID: 26733476
- Serum metabolomics in oral leukoplakia and oral squamous cell carcinoma. | Sridharan, G., et al. 2017. J Cancer Res Ther. 13: 556-561. PMID: 28862226
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-Acetyl-4-aminosalicylic Acid, 1 g | sc-207963 | 1 g | $297.00 |