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N-(4-Hydroxyphenylpropanoyl) spermine trihydrochloride is a wasp toxin analog. More potent than PhTX-343 at locust NMJ. Antagonist of the quis-GluR (quisqualate-sensitive L-glutamate receptor) of locust muscle.
Related products include N-(4-Hydroxyphenylacetyl)-spermine (sc-200466)
Bycroft et al (1990) Invertebrate pharmacological assay of novel, potent glutamate antagonists: acylated spermines. Eur.J.Pharmacol. 183 470. Smith et al (1990) Mono-acylated spermines: antagonists of glutamate receptors. Eur.J.Pharmacol. 183 472.
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