Molecular structure of N-(4-Hydroxyphenylacetyl)-spermine, CAS Number: 130210-32-1
N-(4-Hydroxyphenylacetyl)-spermine (CAS 130210-32-1)
Alternate Names:
N-(N-(4-Hydroxyphenylacetyl)-3-aminopropyl)-(N′-3-aminopropyl)-1,4-butanediamine
Application:
N-(4-Hydroxyphenylacetyl)-spermine is a wasp toxin analog of PhTX-433 that acts as a very potent glutamate antagonist
CAS Number:
130210-32-1
Molecular Weight:
336.5
Molecular Formula:
C18H32N4O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
N-(4-Hydroxyphenylacetyl)-spermine is a wasp toxin analog of naturally occurring PhTX-433. N-(4-Hydroxyphenylacetyl)-spermine is a very potent glutamate antagonist, more potent than PhTX-433at locust NMJ. This has shown to be selective for NMDA receptors in mammalian CNS.
N-(4-Hydroxyphenylacetyl)-spermine (CAS 130210-32-1) References
- Do polyamines regulate the NMDA inhibition of muscarinic receptor-induced phosphoinositide turnover in guinea pig brain? | Alexander, SP., et al. 1991. Neurosci Lett. 131: 167-70. PMID: 1662340
- Spider toxins as tools for dissecting elements of excitatory amino acid transmission. | Jackson, H. and Usherwood, PN. 1988. Trends Neurosci. 11: 278-83. PMID: 2465627
Inhibitor of:
NMDA.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(4-Hydroxyphenylacetyl)-spermine, 250 µg | sc-200466 | 250 µg | $149.00 |