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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea (CAS 330796-24-2) — Molecular structure of N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, CAS Number: 330796-24-2

Molecular structure of N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, CAS Number: 330796-24-2

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea (CAS 330796-24-2)

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Application:

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea is a hedgehog inhibitor

CAS Number:

330796-24-2

Molecular Weight:

490.84

Molecular Formula:

C₂₃H₁₅ClF₄N₄O₂

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data.

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Description

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SDS & Certificate of Analysis

A potent modulator of Hedgehog (Hh) protein function and a nanomolar Hh antagonist.

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea (CAS 330796-24-2) References

Chiang, C., et al.: Nature, 383, 407 (1996), Hahn, H., et al.: Cell, 85, 841 (1996), Johnson, R.L., et al.: Science, 272, 1668 (1996), St.-Jacques, B., et al.: Genes Dev., 13, 2072 (1999),

Inhibitor of:

hedgehog.

Ordering Information

Product Name	Catalog #	UNIT	Price	Qty	FAVORITES
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 1 mg	sc-212054	1 mg	$220.00
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 5 mg	sc-212054A	5 mg	$390.00
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 2 mg	sc-212054B	2 mg	$340.00
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 10 mg	sc-212054C	10 mg	$490.00

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Test	Specification	Results
Appearance	White crystalline powder	Complies
Purity (HPLC)	≥ 98%	> 99.9%
Melting Point		231 - 234 °C

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea (CAS 330796-24-2)

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea (CAS 330796-24-2) References

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N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 1 mg

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 5 mg

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 2 mg

N-[4-Chloro-3-(trifluoromethyl)phenyl]-N′-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl]urea, 10 mg