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![Molecular structure of N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, CAS Number: 299441-52-4 N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide (CAS 299441-52-4) - chemical structure image](https://media.scbt.com/product/n-4-2-amino-1-3-thiazol-4-yl-phenylbenzamide-structure_25_83_t_258302.jpg)
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N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, referred to as GSK-3 inhibitor VIII, is a chemical compound. It has been observed to exhibit inhibitory effects on glycogen synthase kinase-3 (GSK-3), an enzyme involved in multiple signaling pathways governing cell growth, differentiation, and survival. The inhibition of GSK-3 by N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide is achieved through binding to its ATP-binding site, effectively impeding its phosphorylation and subsequent activation. This modulation of GSK-3 activity leads to the alteration of downstream signaling pathways, including the Wnt/β-catenin pathway, the PI3K/Akt pathway, and the NF-κB pathway.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, 250 mg | sc-355233 | 250 mg | $201.00 | |||
N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, 1 g | sc-355233A | 1 g | $407.00 |