Date published: 2025-12-18

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N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide (CAS 299441-52-4)

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CAS Number:
299441-52-4
Molecular Weight:
295.36
Molecular Formula:
C16H13N3OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, referred to as GSK-3 inhibitor VIII, is a chemical compound. It has been observed to exhibit inhibitory effects on glycogen synthase kinase-3 (GSK-3), an enzyme involved in multiple signaling pathways governing cell growth, differentiation, and survival. The inhibition of GSK-3 by N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide is achieved through binding to its ATP-binding site, effectively impeding its phosphorylation and subsequent activation. This modulation of GSK-3 activity leads to the alteration of downstream signaling pathways, including the Wnt/β-catenin pathway, the PI3K/Akt pathway, and the NF-κB pathway.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, 250 mg

sc-355233
250 mg
$201.00

N-[4-(2-amino-1,3-thiazol-4-yl)phenyl]benzamide, 1 g

sc-355233A
1 g
$407.00