Date published: 2026-5-19

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N-(3-Hydroxydodecanoyl)-DL-homoserine lactone (CAS 182359-60-0)

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Alternate Names:
3OH-C12-HSL
Application:
CAS Number:
182359-60-0
Purity:
≥97%
Molecular Weight:
299.41
Molecular Formula:
C16H29NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is an organic molecule utilized in the study of bacterial communication, known as quorum sensing. N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is a type of acyl-homoserine lactone (AHL), which is a signaling molecule in Gram-negative bacteria, facilitating the regulation of gene expression in response to changes in cell-population density. Studies involving N-(3-Hydroxydodecanoyl)-DL-homoserine lactone focuses on its role in the synthesis and detection of AHLs to understand bacterial behavior such as biofilm formation, virulence factor production, and symbiosis. N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is also instrumental in the study of the molecular mechanisms underlying quorum sensing, including the interactions between AHLs and their receptor proteins. N-(3-Hydroxydodecanoyl)-DL-homoserine lactone is deployed in the development of biosensors that are designed to detect the presence of specific AHLs, which can be applied in the monitoring of microbial communities in various environments.


N-(3-Hydroxydodecanoyl)-DL-homoserine lactone (CAS 182359-60-0) References

  1. Orally administered thermostable N-acyl homoserine lactonase from Bacillus sp. strain AI96 attenuates Aeromonas hydrophila infection in zebrafish.  |  Cao, Y., et al. 2012. Appl Environ Microbiol. 78: 1899-908. PMID: 22247159
  2. The role of quorum sensing signalling in EPS production and the assembly of a sludge community into aerobic granules.  |  Tan, CH., et al. 2014. ISME J. 8: 1186-97. PMID: 24430488
  3. Quorum Sensing in a Methane-Oxidizing Bacterium.  |  Puri, AW., et al. 2017. J Bacteriol. 199: PMID: 27994019
  4. Community quorum sensing signalling and quenching: microbial granular biofilm assembly.  |  Tan, CH., et al. 2015. NPJ Biofilms Microbiomes. 1: 15006. PMID: 28721230
  5. Unsaturated Fatty Acids Affect Quorum Sensing Communication System and Inhibit Motility and Biofilm Formation of Acinetobacter baumannii.  |  Nicol, M., et al. 2018. Int J Mol Sci. 19: PMID: 29320462
  6. Detection of New Quorum Sensing N-Acyl Homoserine Lactones From Aeromonas veronii.  |  Gui, M., et al. 2018. Front Microbiol. 9: 1712. PMID: 30108567
  7. Interspecies Chemical Signaling in a Methane-Oxidizing Bacterial Community.  |  Puri, AW., et al. 2019. Appl Environ Microbiol. 85: PMID: 30709826
  8. Mechanism Underlying the Role of LuxR Family Transcriptional Regulator abaR in Biofilm Formation by Acinetobacter baumannii.  |  Sun, X. and Xiang, J. 2021. Curr Microbiol. 78: 3936-3944. PMID: 34522977

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-(3-Hydroxydodecanoyl)-DL-homoserine lactone, 25 mg

sc-396655
25 mg
$173.00