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N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala (CAS 78832-65-2)

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Alternate Names:
FALGPA
Application:
N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala is a substrate for the spectrophotometric assay of MMP (collagenase)
CAS Number:
78832-65-2
Molecular Weight:
476.52
Molecular Formula:
C23H32N4O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala (FALGPA) is a substrate for the spectrophotometric assay of MMP (collagenase). The isoforms I and II of purified collagenase differ in their specificities and relative activities on native collagen and synthetic substrates. Collagenase II activity is measured by the enzyme′s ability to cut a short synthetic peptide, N-[3-(2-Furyl)acryloyl)]-Leu-Gly- Pro-Ala (FALGPA).


N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala (CAS 78832-65-2) References

  1. Characterization of a novel PepF-like oligopeptidase secreted by Bacillus amyloliquefaciens 23-7A.  |  Chao, SH., et al. 2006. Appl Environ Microbiol. 72: 968-71. PMID: 16391147
  2. An internally quenched fluorescent substrate for collagenase.  |  Saikumari, YK. and Balaram, P. 2008. Biopolymers. 90: 131-7. PMID: 18260138
  3. Anti-collagenase, anti-elastase and anti-oxidant activities of extracts from 21 plants.  |  Thring, TS., et al. 2009. BMC Complement Altern Med. 9: 27. PMID: 19653897
  4. Antioxidant and potential anti-inflammatory activity of extracts and formulations of white tea, rose, and witch hazel on primary human dermal fibroblast cells.  |  Thring, TS., et al. 2011. J Inflamm (Lond). 8: 27. PMID: 21995704
  5. The efficacy and safety of platelet-rich plasma and adipose-derived stem cells: an update.  |  Choi, J., et al. 2012. Arch Plast Surg. 39: 585-92. PMID: 23233882
  6. Proteomic protease specificity profiling of clostridial collagenases reveals their intrinsic nature as dedicated degraders of collagen.  |  Eckhard, U., et al. 2014. J Proteomics. 100: 102-14. PMID: 24125730
  7. Thai plants with high antioxidant levels, free radical scavenging activity, anti-tyrosinase and anti-collagenase activity.  |  Chatatikun, M. and Chiabchalard, A. 2017. BMC Complement Altern Med. 17: 487. PMID: 29121910
  8. Reduced synovial inflammation and inhibition of matrix metalloproteinases explicates anti-osteoarthritis activity of polyherbal formulations.  |  Ingale, DR., et al. 2018. Indian J Pharmacol. 50: 22-29. PMID: 29861524
  9. Vancomycin-loaded chitosan aerogel particles for chronic wound applications.  |  López-Iglesias, C., et al. 2019. Carbohydr Polym. 204: 223-231. PMID: 30366534
  10. Inhibitory role of silk cocoon extract against elastase, hyaluronidase and UV radiation-induced matrix metalloproteinase expression in human dermal fibroblasts and keratinocytes.  |  Kumar, JP. and Mandal, BB. 2019. Photochem Photobiol Sci. 18: 1259-1274. PMID: 30891584
  11. A continuous spectrophotometric assay for Clostridium histolyticum collagenase.  |  Van Wart, HE. and Steinbrink, DR. 1981. Anal Biochem. 113: 356-65. PMID: 6269461
  12. Characterization of PepB, a group B streptococcal oligopeptidase.  |  Lin, B., et al. 1996. Infect Immun. 64: 3401-6. PMID: 8757883
  13. Inhibitory properties of the antibothropic complex from the South American opossum (Didelphis marsupialis) serum.  |  Neves-Ferreira, AG., et al. 1997. Toxicon. 35: 849-63. PMID: 9241780

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, 5 mg

sc-253087
5 mg
$122.00

N-[3-(2-Furyl)acryloyl]-Leu-Gly-Pro-Ala, 25 mg

sc-253087A
25 mg
$447.00