Molecular structure of N-(2-Hydroxyethyl)succinimide, CAS Number: 18190-44-8
N-(2-Hydroxyethyl)succinimide (CAS 18190-44-8)
CAS Number:
18190-44-8
Molecular Weight:
143.14
Molecular Formula:
C6H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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N-(2-Hydroxyethyl)succinimide functions as a reactive intermediate in chemical synthesis. It acts as a nucleophile in organic reactions, particularly in the formation of amide bonds. N-(2-Hydroxyethyl)Succinimide is known to participate in the modification of proteins and peptides through succinimide ring opening, allowing for the introduction of various functional groups. Its mechanism of action involves the formation of covalent bonds with amino acid residues, leading to the conjugation of other molecules or polymers. Its reactivity and ability to modify biomolecules make it useful in the study of protein chemistry and bioconjugation techniques.
N-(2-Hydroxyethyl)succinimide (CAS 18190-44-8) References
- A novel bifunctional metabolizable linker for the conjugation of antibodies with radionuclides. | Arano, Y., et al. 1991. Bioconjug Chem. 2: 71-6. PMID: 1868115
- A new synthesis and crystal structure of n-(2-hydroxyethyl)succinimide | Maija Pitkänen a, Ilkka Pitkänen a 1, Hans-Erik Eriksson, Pekka Autio a. 1988. Tetrahedron. 44: 261-265.
- Synthesis and characterization of polypropylene-based polymer hybrids linking poly(methyl methacrylate) and poly(2-hydroxyethyl methacrylate) | Hideyuki Kaneko, Junji Saito, Nobuo Kawahara, Shingo Matsuo, Tomoaki Matsugi, Norio Kashiwa. 2008. Polymer. 49: 4576-4584.
- Conformational, spectroscopic (FT-IR, FT-Raman, and UV-Vis), and molecular docking studies of N-(2-hydroxyethyl) succinimide | A. Eşme a, S.G. Sagdinc b. 2019. Journal of Molecular Structure. 1195: 451-461.
- Synthesis and biological evaluation of new silicon(IV) phthalocyanines as carbonic anhydrase and cholinesterase inhibitors | Volkan Çakır a, Tayfun Arslan b. 2022. Inorganica Chimica Acta. 530.
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(2-Hydroxyethyl)succinimide, 5 g | sc-228628 | 5 g | $17.00 |