N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide CAS: 302964-08-5
MF: C16H13Cl2N5OS
MW: 394.28
A protein tyrosine kinase inhibitor and Dasatinib intermediate.

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5)

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Synonym: 2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; 2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide
Application: A protein tyrosine kinase inhibitor and Dasatinib intermediate
CAS Number: 302964-08-5
Purity: 98%
Molecular Weight: 394.28
Molecular Formula: C16H13Cl2N5OS
* Refer to Certificate of Analysis for lot specific data (including water content).
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N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamidea Dasatinib intermediate and a protein Tyk (tyrosine kinase) inhibitor.


1. Fitzer-Attas, C., et al. 2000. J. Exp. Med. 191: 669-682. PMID: 10684859
2. Das, J., et al. 2003. Bioorg. Med. Chem. Lett. 13: 2587-2590. PMID: 12852972
3. Chen, P., et al. 2004. J. Med. Chem. 47: 4517-4529. PMID: 15317463

Physical State :
Solubility :
Soluble in DMSO, and water (slightly).
Storage :
Store at 4° C
Melting Point :
>260° C (dec.)
Boiling Point :
566.95° C (Predicted)
Density :
1.52 g/cm3 (Predicted)
Refractive Index :
n20D 1.72 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :

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Certificate of Analysis

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