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N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5) - chemical str — Molecular structure of N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, CAS Number: 302964-08-5

Molecular structure of N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, CAS Number: 302964-08-5

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5)

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Alternate Names:

2-((6-Chloro-2-methylpyrimidin-4-yl)amino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; 2-(6-chloro-2-methylpyrimidin-4-ylamino)-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide; N-(2-chloro-6-methylphenyl)-2-[(6-chloro-2-methylpyrimidin-4-yl)amino]-1,3-thiazole-5-carboxamide

Application:

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide is a protein tyrosine kinase inhibitor and Dasatinib intermediate

CAS Number:

302964-08-5

Purity:

98%

Molecular Weight:

394.28

Molecular Formula:

C₁₆H₁₃Cl₂N₅OS

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

* Refer to Certificate of Analysis for lot specific data.

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Description

Technical Information

Safety Information

SDS & Certificate of Analysis

Protein tyrosine kinase inhibitor. Dasatinib intermediate.

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5) References

Fitzer-Attas, C., et al.: J. Exp. Med., 191, 669 (2000), Das, J., et al.: Bioorg. Med. Chem. Lett., 13, 2587 (2003), Chen, P., et al.: J. Med. Chem., 47, 4517 (2004).

Inhibitor of:

Tyk.

Ordering Information

Product Name	Catalog #	UNIT	Price	Qty	FAVORITES
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 250 mg	sc-207904	250 mg	$178.00
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 500 mg	sc-207904A	500 mg	$260.00
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 1 g	sc-207904B	1 g	$420.00
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 10 g	sc-207904C	10 g	$940.00
N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 100 g	sc-207904D	100 g	$1800.00

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Test	Specification	Results
Appearance	Yellow to pale yellow solid	Complies
Identification (Infrared Spectrum)	Conforms to structure	Complies
Purity (HPLC)	≥98%	99.4%
Residue on evaporation	≤0.2%	0.12%
Loss on Drying	≤1.0%	0.16%

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5)

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide (CAS 302964-08-5) References

SAMPLE Certificate of Analysis (COA)

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N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 250 mg

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 500 mg

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 1 g

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 10 g

N-(2-Chloro-6-methylphenyl)-2-[(6-chloro-2-methyl-4-pyrimidinyl)amino]-5-thiazolecarboxamide, 100 g