Molecular structure of N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride, CAS Number: 84468-17-7
N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride (CAS 84468-17-7)
Alternate Names:
H-9
CAS Number:
84468-17-7
Molecular Weight:
324.22
Molecular Formula:
C11H13N3O2S•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Protein kinase inhibitor most effective for cAMP and cGMP dependent protein kinases.
N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride (CAS 84468-17-7) References
- PKCalpha mediates TGFbeta-induced growth inhibition of human keratinocytes via phosphorylation of S100C/A11. | Sakaguchi, M., et al. 2004. J Cell Biol. 164: 979-84. PMID: 15051732
- Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones. | Holohean, AM. and Hackman, JC. 2004. Br J Pharmacol. 143: 351-60. PMID: 15339859
- Protein kinase C inhibitors enhance concanavalin A cap formation in polymorphonuclear leukocytes. | Sato, A., et al. 1990. Int J Immunopharmacol. 12: 121-5. PMID: 2105914
- Delay of iris flower senescence by cytokinins and jasmonates. | van Doorn, WG., et al. 2013. Physiol Plant. 148: 105-20. PMID: 22974423
- N-(2-Aminoethyl)-5-isoquinolinesulfonamide, a newly synthesized protein kinase inhibitor, functions as a ligand in affinity chromatography. Purification of Ca2+-activated, phospholipid-dependent and other protein kinases. | Inagaki, M., et al. 1985. J Biol Chem. 260: 2922-5. PMID: 2982842
- A potent inhibitor of protein kinase C inhibits natural killer activity. | Ito, M., et al. 1988. Int J Immunopharmacol. 10: 211-6. PMID: 3182150
- Interaction of protein kinase C with membranes is regulated by Ca2+, phorbol esters, and ATP. | Wolf, M., et al. 1985. J Biol Chem. 260: 15718-22. PMID: 4066694
- Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C. | Hidaka, H., et al. 1984. Biochemistry. 23: 5036-41. PMID: 6238627
- Purification and biochemical characterization of the protein kinase encoded by the US3 gene of herpes simplex virus type 2. | Daikoku, T., et al. 1993. Virology. 197: 685-94. PMID: 8249291
- Protein kinase modulation of GABAA currents in rabbit retinal rod bipolar cells. | Gillette, MA. and Dacheux, RF. 1996. J Neurophysiol. 76: 3070-86. PMID: 8930256
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride, 10 mg | sc-358380 | 10 mg | $99.00 | |||
N-(2-Aminoethyl)-5-isoquinolinesulfonamide dihydrochloride, 25 mg | sc-358380A | 25 mg | $268.00 |