Date published: 2025-11-15

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Myristic Acid (CAS 544-63-8)

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Alternate Names:
Tetradecanoic Acid
Application:
Myristic Acid is a 14 carbon saturated fatty acid
CAS Number:
544-63-8
Purity:
98%
Molecular Weight:
228.4
Molecular Formula:
C14H28O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Myristic Acid, a saturated fatty acid consisting of 14 carbon atoms, plays a unique role in cellular processes as a substrate for certain fatty acid desaturases. Commonly found in animal and vegetable fats, myristic acid is integral to various biological functions, including cell membrane formation, signal transduction, and energy metabolism. Its synthesis from other fatty acids is for generating a diverse range of products, such as pharmaceuticals, food additives, and cosmetics. The scientific applications of myristic acid encompass a broad spectrum of research areas. It serves as a tool for investigating the impact of fatty acid metabolism on the body and the role of fatty acids in signal transduction and cell membrane formation. Moreover, myristic acid enables the exploration of how fatty acids influence the structure and function of proteins and enzymes. Through a process known as N-terminal myristoylation, myristic acid can acylate proteins by covalently binding to N-terminal glycine residues, which activates and mediates numerous physiological pathways. Furthermore, saturated fatty acids, including myristic acid, have been observed to be vital for the biological activities of lipopolysaccharides. They can also induce the expression of COX-2 and activate NFκB (nuclear factor κB). In summary, myristic acid plays an essential role in diverse biological processes and serves as useful in scientific research to elucidate its effects and implications.


Myristic Acid (CAS 544-63-8) References

  1. Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.  |  Lee, JY., et al. 2001. J Biol Chem. 276: 16683-9. PMID: 11278967
  2. Safety assessment of myristic acid as a food ingredient.  |  Burdock, GA. and Carabin, IG. 2007. Food Chem Toxicol. 45: 517-29. PMID: 17141389
  3. [New regulatory and signal functions for myristic acid].  |  Beauchamp, E., et al. 2009. Med Sci (Paris). 25: 57-63. PMID: 19154695
  4. Final report of the amended safety assessment of myristic acid and its salts and esters as used in cosmetics.  |  Becker, LC., et al. 2010. Int J Toxicol. 29: 162S-86S. PMID: 20634506
  5. Regulation of mammalian desaturases by myristic acid: N-terminal myristoylation and other modulations.  |  Rioux, V., et al. 2011. Biochim Biophys Acta. 1811: 1-8. PMID: 20920594
  6. Myristic Acid Enhances Diacylglycerol Kinase δ-Dependent Glucose Uptake in Myotubes.  |  Wada, Y., et al. 2016. Lipids. 51: 897-903. PMID: 27206979
  7. Myristic acid in amniotic fluid produces appetitive responses in human newborns.  |  Gutiérrez-García, AG., et al. 2017. Early Hum Dev. 115: 32-37. PMID: 28886572
  8. Photoactivatable Myristic Acid Probes for UNC119-Cargo Interactions.  |  Kaiser, N., et al. 2019. Chembiochem. 20: 134-139. PMID: 30129686
  9. Antimicrobial potential of myristic acid against Listeria monocytogenes in milk.  |  Chen, X., et al. 2019. J Antibiot (Tokyo). 72: 298-305. PMID: 30787402
  10. Kinetics of Myristic Acid Following Accidentally Induced Septic Response.  |  Zazula, R., et al. 2019. Prague Med Rep. 120: 103-106. PMID: 31586509
  11. The Myristic Acid:Docosahexaenoic Acid Ratio Versus the n-6 Polyunsaturated Fatty Acid:n-3 Polyunsaturated Fatty Acid Ratio as Nonalcoholic Fatty Liver Disease Biomarkers.  |  Masetto Antunes, M., et al. 2022. Metab Syndr Relat Disord. 20: 69-78. PMID: 34813379
  12. Myristic Acid Inhibits the Activity of the Bacterial ABC Transporter BmrA.  |  Oepen, K., et al. 2021. Int J Mol Sci. 22: PMID: 34948362
  13. Myristic acid selectively augments β-tubulin levels in C2C12 myotubes via diacylglycerol kinase δ.  |  Sakai, H., et al. 2022. FEBS Open Bio. 12: 1788-1796. PMID: 35856166

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Myristic Acid, 1 g

sc-205393
1 g
$30.00

Myristic Acid, 5 g

sc-205393A
5 g
$75.00

Myristic Acid, 50 g

sc-205393B
50 g
$300.00