MyosmineA specific tobacco alkaloid

Myosmine (CAS 532-12-7)

Myosmine | CAS 532-12-7 is rated 5.0 out of 5 by 1.
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Synonym: 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine
Application: A specific tobacco alkaloid
CAS Number: 532-12-7
Purity: 98%
Molecular Weight: 146.19
Molecular Formula: C9H10N2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Myosmine is a minor tobacco alkaloid which has been shown to possess genotoxic effects on cells through DNA damage by pyridyloxobutylation. Studies indicate that in cells Myosmine can be activated into reactive intermediates by H2O2 (sc-203336) and 3-morpholinosydnonimine (sc-200339). It is known that under acidic pH Myosmine undergoes a ring-chain tautomerism and is present in the amino-keto form. Furthermore, Myosmine is an ideal tool to use to monitor the effects of tobacco smoke on cells.


References

1. Zwickenpflug, W. and Tyroller, S. 2006. Chem. Res. Toxicol. 19: 150-155. PMID: 16411668
2. Havla, J.B., et al. 2009. Food Chem. Toxicol. 47: 237-241. PMID: 19041922
3. Jiang, E., et al. 2009. Mutat. Res. 672: 60-64. PMID: 19007910

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in Ether, Ethyl Acetate, Methanol and Water
Storage :
Store at 4° C
Melting Point :
42-44° C
Boiling Point :
82-83° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
442649
MDL Number :
MFCD00052019
Beilstein Registry :
119254
SMILES :
C1CN=C(C1)C1=CC=CN=C1

Download SDS (MSDS)

Certificate of Analysis

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We are interested in 2-kilos of pure Myosmine. Please advise best price and terms

Asked by: Ashok
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Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Moghbel Moghbel, N. et al. (PubMed 26114650) developed a reversed-phase HPLC-UV method for the separation and quantitation of six target alkaloids from leaves of Nicotiana species (nicotine, nornicotine, anatabine, anabasine, Myosmine, and cotinine). -SCBT Publication Review
Date published: 2015-02-06
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