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myo-Inositol hexasulfate hexapotassium salt (CAS 28434-25-5)

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Alternate Names:
Inositol hexakissulfate
Application:
myo-Inositol hexasulfate hexapotassium salt is an inhibitor of Aspergillus phytase
CAS Number:
28434-25-5
Purity:
≥95%
Molecular Weight:
889.08
Molecular Formula:
C6H6O24S66K
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Myo-Inositol hexasulfate hexapotassium salt plays a functional role in cellular signaling and regulation. It interacts with cellular components by binding to specific receptors on the cell membrane, thereby initiating a cascade of intracellular signaling events. This compound modulates the activity of various enzymes and transcription factors, influencing key cellular processes such as cell growth, differentiation, and apoptosis. Additionally, myo-Inositol hexasulfate hexapotassium salt regulates the uptake and utilization of glucose and other nutrients by cells, thereby impacting cellular metabolism. Its mechanism of action involves the activation of protein kinase pathways and the modulation of ion channels, ultimately leading to the regulation of gene expression and cellular function. Overall, myo-Inositol hexasulfate hexapotassium salt exerts its influence on cellular processes and pathways through its interactions with specific molecular targets, ultimately contributing to the maintenance of cellular homeostasis and function.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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myo-Inositol hexasulfate hexapotassium salt (CAS 28434-25-5) References

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  2. Energetics of myo-inositol hexasulfate binding to human acidic fibroblast growth factor effect of ionic strength and temperature.  |  Guzmán-Casado, M., et al. 2000. Eur J Biochem. 267: 3477-86. PMID: 10848963
  3. Assessing the omnipotence of inositol hexakisphosphate.  |  Shears, SB. 2001. Cell Signal. 13: 151-8. PMID: 11282453
  4. Cloned and expressed fungal phyA gene in alfalfa produces a stable phytase.  |  Ullah, AH., et al. 2002. Biochem Biophys Res Commun. 290: 1343-8. PMID: 11812011
  5. PhyA gene product of Aspergillus ficuum and Peniophora lycii produces dissimilar phytases.  |  Ullah, AH. and Sethumadhavan, K. 2003. Biochem Biophys Res Commun. 303: 463-8. PMID: 12659840
  6. Fungal phyA gene expressed in potato leaves produces active and stable phytase.  |  Ullah, AH., et al. 2003. Biochem Biophys Res Commun. 306: 603-9. PMID: 12804608
  7. INOSITOL HEXASULFATE, A NON-COMPETITIVE INHIBITOR OF ACID PHOSPHATASE FROM WHEAT BRAN.  |  NAGAI, Y., et al. 1963. J Biochem. 54: 191-2. PMID: 14060395
  8. Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis.  |  Chu, HM., et al. 2004. Structure. 12: 2015-24. PMID: 15530366
  9. Crystal structures of Bacillus alkaline phytase in complex with divalent metal ions and inositol hexasulfate.  |  Zeng, YF., et al. 2011. J Mol Biol. 409: 214-24. PMID: 21463636
  10. Interactions of phytate and myo-inositol phosphate esters (IP1-5) including IP5 isomers with dietary protein and iron and inhibition of pepsin.  |  Yu, S., et al. 2012. J Anim Sci. 90: 1824-32. PMID: 22228039
  11. Involvement of phosphatidylinositol and insulin in the coordinate regulation of proteoheparan sulfate metabolism and hepatocyte growth.  |  Ishihara, M., et al. 1987. J Biol Chem. 262: 4708-16. PMID: 2951371
  12. Characterization of IMT1, myo-inositol O-methyltransferase, from Mesembryanthemum crystallinum.  |  Rammesmayer, G., et al. 1995. Arch Biochem Biophys. 322: 183-8. PMID: 7574673
  13. Myo-inositol hexasulfate is a potent inhibitor of Aspergillus ficuum phytase.  |  Ullah, AH. and Sethumadhavan, K. 1998. Biochem Biophys Res Commun. 251: 260-3. PMID: 9790943

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

myo-Inositol hexasulfate hexapotassium salt, 25 mg

sc-215406
25 mg
$214.00

myo-Inositol hexasulfate hexapotassium salt, 250 mg

sc-215406A
250 mg
$714.00